CAS 64-19-7 Glacial acetic acid (GAA), a high-purity form of anhydrous acetic acid, typically exceeding 99% purity, is widely used as a key raw material, solvent, and chemical intermediate in numerous industrial sectors. Due to its strong acidity, high reactivity, and excellent solubility, glacial acetic acid plays a crucial role in chemical synthesis, manufacturing processes, and large-scale industrial production.
What Is Glacial acetic acid CAS 64-19-7?
Glacial acetic acid is essentially pure anhydrous acetic acid. Undiluted, it is a colorless liquid that solidifies into ice-like crystals at temperatures below 16.6°C.
Unlike diluted acetic acid, GAA typically has a purity greater than 99%. This high purity gives it extremely high reactivity, making it suitable for industrial applications, but its corrosiveness requires careful handling.

How is Glacial Acetic Acid produced?
There are two main routes:
The first, and currently the most widely used industrial method, is the methanol carbonylation method. This method involves the reaction of methanol with carbon monoxide under catalytic conditions to produce acetic acid.
The second method is bio-fermentation. Its principle is similar to vinegar brewing, but the process is optimized. This yields acetic acid with higher purity, but further refining is still required.
Regardless of the production route used, the resulting crude acetic acid needs additional purification steps, such as moisture removal, before it can be used to produce glacial acetic acid.
Key Properties of gAA
| Chemical Name | Glacial Acetic Acid |
| CAS Number | 64-19-7 |
| Molecular Formula | CH₃COOH |
| Molecular Weight | 60.05 g/mol |
| Appearance | Colorless transparent liquid |
| Odor | Strong pungent vinegar-like smell |
| Purity | ≥99% (industrial grade) |
| Melting Point | 16.6°C |
| Boiling Point | 117.9°C |
| Density | ~1.049 g/cm³ at 25°C |
| Solubility | Fully miscible with water, alcohol, ether |
| Flammability | Flammable liquid |
glacial acetic acid uses in industry
Glacial acetic acid has a wide range of applications in numerous industrial sectors. Its main applications include:
1. Chemical Production and Plastics Industry
High Purity Glacial Acetic Acid is an important raw material for many chemical intermediates and polymer compounds. It is used to manufacture vinyl acetate monomer (VAM), an essential raw material for polyvinyl acetate (PVA), which is a common raw material for paints, adhesives, and various coatings.
In plastics and resin manufacturing, glacial acetic acid is used to produce cellulose acetate for films and textile fibers. It is also used to produce purified terephthalic acid (PTA), a core raw material for manufacturing PET plastic containers for beverage and food packaging.
2. Pharmaceutical and Healthcare Industry
99.5% Glacial acetic acid has high purity and good chemical reactivity, making it suitable as a chemical reagent and polar proton solvent in drug synthesis processes. In API production, GAA is an important solvent and catalyst used in the production of many commonly used drugs, including aspirin, vitamins, hormones, and antibiotics.
3. Textile Printing and Dyeing Processing
Acetic acid (Glacial) is widely used in the textile industry. It can be used as a neutralizing agent and pH adjuster. Furthermore, it is suitable for processing cellulose acetate fibers, contributing to the production of lustrous synthetic textiles.
4. Industrial Cleaning and Disinfection
Glacial acetic acid (CAS 64-19-7) is a strong acid with bactericidal activity, making it a reliable commercial cleaning agent. It can also be used for surface disinfection in food processing plants, as well as for cleaning and disinfecting laboratory and medical devices.
5. Food and Agrochemical Industries
CAS 64-19-7 Glacial acetic acid, after appropriate dilution, can be used as food additive E260, as an acidity regulator and preservative in pickles, sauces, and other condiments. In the agrochemical field, it is also an important intermediate in the synthesis of certain herbicides and pesticides.
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Safety and Handling of Industrial acetic acid
Glacial acetic acid liquid is corrosive and must be handled with care. Wear protective gloves and goggles during handling, and ensure good ventilation. Avoid direct skin contact and keep away from heat and oxidizers. GAA should be stored in a cool, dry place in a tightly closed container.
For more information on purchasing industrial-grade glacial acetic acid, please consult Gneebio Chemicals Supplier.
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Gneebio Product Packaging
| Packaging Type | Net Weight |
|---|---|
| Steel Drum | 250 kg |
| IBC Tank | 1250 kg |
| ISO Tank | Bulk shipment |

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