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How is DMF solvent used in pharmaceuticals? - CAS 68-12-2 N,N-Dimethylformamide

Jan 12, 2026 Leave a message

what is DMF solvent CAS 68-12-2?

Dimethylformamide (DMF) is an organic solvent commonly used in various industrial and laboratory applications. It is a colorless, hygroscopic liquid with a distinctive odor, known for its ability to dissolve a wide range of substances, making it a versatile solvent in chemical processes.

 

Name DMF
The Molecular Formula of the Chemical C₃H₇NO
Physical Appearance of the Chemical Colorless, Hygroscopic Liquid
Melting Point -61°C (-78°F)
Cas No. 68-12-2
Synonyms Dimethylformamide; N,N-Dimethylformamide

 

How is DMF solvent used in pharmaceuticals?

Dimethylformamide DMF solvent is of great importance to the pharmaceutical industry. It acts as a solvent for the synthesis of active pharmaceutical ingredients. Due to its polar, aprotic nature, it dissolves both polar and non-polar substances and facilitates many reactions used in drug production and drug development.

 

In the pharmaceutical industry, high-purity DMF is indispensable as a reaction solvent due to its high polarity, thermal stability, and excellent solvating power. It facilitates a wide array of chemical reactions (e.g., condensations, cyclizations, coupling reactions) in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs). Its ability to dissolve both organic and inorganic compounds makes it ideal for multi-step synthesis processes.
 

 

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