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How is phthalic anhydride produced from o-xylene?

Jan 28, 2026 Leave a message

What Is o-Xylene (CAS 95-47-6)?

Phthalic anhydride (C8​H4​O3​) is manufactured through the catalytic vapor-phase oxidation of o-xylene (CAS 95-47-6) (C8​H10​) with air, carried out in a fixed-bed, multi-tubular reactor. The process uses a catalyst composed of vanadium pentoxide (V2​O5​) and titanium dioxide (TiO2​), operating at a temperature of 340–450°C. The core chemical reaction is:

C8​H10​+3O2​→C8​H4​O3​+3H2​O

 

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o-Xylene (ortho-xylene) Properties

Physical Properties  
Molecular weight 106.17
Boiling point 144.41°C
Vapor pressure 6 Torr at 20°C
Freezing point -25.18°C
Refractive index 1.5054 at 20°C
Density 0.8802 g/mL (7.346 lb/gal) at 20°C
  0.8760 g/mL (7.311 lb/gal) at 25°C
Dielectric constant 2.57 at 20°C
Dipole moment 0.45 D at 25°C
Solvent group 7
Polarity index (P') 2.5
Eluotropic value on alumina 0.26
Viscosity 0.81 cP at 20°C
Surface tension 30.03 dyn/cm at 20°C
Solubility in water 0.018% at 25°C
   
Regulatory and Safety Data  
DOT Hazard Class 3, Flammable Liquid
Packing Group II
UN Identification Number UN1307

 

 

O-xylene is used as a feedstock for phthalic anhydride production:
- It is used to manufacture plasticisers (for PVC) and polyester and alkyd resins.

 

 

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