Is dimethylacetamide (DMAC) hazardous?
CAS 127-19-5 Dimethylacetamide (DMAC) is a hazardous flammable liquid with a flash point of 63-70°C. This substance is classified as a reproductive toxin and may cause harm to the fetus. It poses risks through inhalation or skin absorption. It can severely irritate the eyes, damage the liver, and depress the central nervous system. Special protective measures must be taken, such as operating within a fume hood and wearing appropriate personal protective equipment (PPE).

Primary Health Risks and Effects
- Reproductive hazards: May impair fertility or cause fetal damage.
- Acute toxicity: Hazardous through inhalation or skin contact.
- Affected Organs: Primarily damages the liver, central nervous system, eyes, and skin.
- Symptoms: Inhalation of DMAC vapors may cause headaches, nausea, drowsiness, dizziness, confusion, and vomiting. Skin or eye contact may cause irritation; prolonged exposure may lead to dermatitis.
- Exposure Routes: Vapors or mists may be inhaled through the respiratory tract; absorption through skin is possible; accidental ingestion also poses a risk.
Safety Handling
- Engineering Controls: Use DMAC only in well-ventilated areas. Prioritize chemical fume hoods during operations.
- Personal Protective Equipment (PPE): Wear butyl or nitrile gloves, safety goggles, and protective clothing.
- Key Operating Points: Avoid inhaling vapors or mists; prevent skin and eye contact. Keep away from heat sources, sparks, open flames, and hot surfaces; smoking is strictly prohibited in the vicinity.
As a professional DMAC manufacturer and supplier, we provide industrial and pharmaceutical grade Dimethylacetamide with stable quality, bulk supply capability and full export documentation.
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As a leading manufacturer and exporter of fine chemicals, Henan Gneebio provides high-quality industrial chemicals. We supply to customers across the chemical, pharmaceutical, and materials industries, ensuring consistent quality, reliable logistics, and professional technical support.
Our chemical products hold international certifications (REACH, ISO, FMQS, HALAL) for global quality recognitio. We have warehouses in coreports such as Qingdao, Tianiin, and Shanghai, with a 15-day express delivery service.
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