Dichloromethane (DCM, CAS 75-09-2) is a widely used industrial solvent, but it presents several safety hazards, mainly related to toxicity, vapor inhalation, and long-term health risks.
Dichloromethane DCM solvent can also be absorbed into the body via inhalation, ingestion or skin contact. Symptoms include headache, light-headedness, blurred vision, confusion, agitation and skin rashes. In severe cases kidney damage, fitting, heart problems and coma can occur.
Dichloromethane (DCM) solvent uses
Dichloromethane DCM solvent is widely used in various industries due to its unique properties. Common applications include:
- Pharmaceuticals: Methylene chloride is used as a solvent in the synthesis and extraction of active pharmaceutical ingredients (APIs).
- Paint and Coating Removal: Effective for stripping paint, varnish, and coatings from surfaces.
- Chemical Processing: Utilized in the production of adhesives, plastics, and synthetic fibers.
- Food and Beverage Industry: Dichloromethane liquid is used for decaffeination of coffee and tea (under strict regulatory controls).

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What are the safety hazards of dichloromethane chemical?
1. Inhalation Risk
Dichloromethane DCM evaporates quickly and produces vapors that can be harmful when inhaled.
Possible effects include:
- dizziness
- headache
- nausea
- central nervous system depression
Control Measures:
- Use local exhaust ventilation systems
- Operate in closed or semi-closed systems where possible
- Wear appropriate respirators
2. Toxicity and Health Effects
Dichloromethane solvent can be absorbed through inhalation and skin contact.
Long-term or high-level exposure may affect:
- liver function
- respiratory system
- nervous system
Control Measures:
- Implement workplace exposure monitoring
- Follow occupational exposure limits (OELs)
- Ensure workers receive safety training
3. Skin and Eye Irritation
Direct contact with DCM solvent may cause:
- skin irritation
- dryness or chemical burns (prolonged exposure)
- eye irritation
Control Measures:
- Wear chemical-resistant gloves (e.g., nitrile or Viton)
- Use protective goggles or face shields
- Avoid direct splashing and contact
4. High Volatility
Methylene chloride chemical has a low boiling point (~39.6°C) and high vapor pressure, meaning:
- it evaporates quickly
- vapors can accumulate in the air
Control Measures:
- Store and use in well-ventilated areas
- Keep containers tightly sealed when not in use
- Reduce open handling time
- Use automated or closed transfer systems
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