N,N-Dimethylformamide DMF CAS 68-12-2 is a colorless to yellow transparent liquid with high boiling point with a faint, specific amine-like odor. It is miscible with water. DMF is hydrophilic and polar aprotic solvent, which could increase the SN2 reaction. Existing with strong alkali or acide (especially at high temperature), DEHA hydrolyses into formic acid and dimethylallylamine.
What does dimethylformamide DMF liquid dissolve?
CAS 68-12-2 Dimethylformamide (DMF) is a versatile solvent that dissolves many organic substances, particularly polar polymers such as polyvinyl chloride, polyacrylonitrile and polyurethanes. This makes DMF liquid essential for producing fibres, films and coatings.
Details as follows:
- Polymers: Polyacrylonitrile, polyurethanes, polyvinyl chloride (PVC), polyimides.
- Organic Compounds: Most polar and many non-polar organic molecules.
- Inorganic Compounds: Many salts, such as lithium chloride, calcium chloride, and various metal complexes.
- Gases: It has good solubility for gases like carbon dioxide and hydrogen sulfide.

Toxicity of DMF liquid
N,N-Dimethylformamide DMF liquid has some toxicity to humans. Short-term or long-term exposure can damage the respiratory system, liver, and kidneys. Furthermore, DMF has the potential to cause toxicity through skin absorption. Therefore, care should be taken to avoid direct contact with skin and eyes, and to avoid inhaling its vapors.
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