What Is the Difference Between DMAC and DMF?
DMAC (N,N-Dimethylacetamide) and DMF (N,N-Dimethylformamide) are both widely used polar aprotic solvents in chemical, pharmaceutical, and polymer industries. Although they have similar solvency performance, they differ in chemical structure, thermal stability, and regulatory profile, which matters for industrial buyers.
| Item | DMAC | DMF |
|---|---|---|
| Full Name | N,N-Dimethylacetamide | N,N-Dimethylformamide |
| Abbreviation | DMAC / DMAc | DMF |
| CAS Number | 127-19-5 | 68-12-2 |
| Molecular Formula | C₄H₉NO | C₃H₇NO |
| Boiling Point | ~165 °C | ~153 °C |
| Polarity | Very high | Very high |
| Water Miscibility | Fully miscible | Fully miscible |
| Thermal Stability | Higher | Slightly lower |
Applications Difference
N,N-Dimethylacetamide DMAC Uses
Polyurethane (PU) and acrylic fiber production
Pharmaceutical synthesis
Lithium-ion battery materials
High-performance coatings and resins
N,N-Dimethylformamide DMF Uses
Pharmaceutical intermediates
Synthetic leather (PU coating)
Agrochemicals
Dyes and pigments
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