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What Is the Difference Between MEG and Propylene Glycol?

Jan 30, 2026 Leave a message

What Is the Difference Between MEG and Propylene Glycol?

The primary difference between Mono Ethylene Glycol (MEG) and Propylene Glycol (PG) is that MEG is highly toxic and best for industrial cooling, while PG is non-toxic, safe for human consumption, and used in food/pharma applications.

 

Mono Ethylene Glycol (MEG)

  • Toxicity: Highly toxic, requiring strict handling.
  • Best Use: Industrial applications, automotive antifreeze, de-icing, and PET plastic production.
  • Performance: Lower viscosity and better heat transfer efficiency than PG.
  • Cost: Generally cheaper than PG.

 

Propylene Glycol (PG)

  • Toxicity: Non-toxic, safe for human and animal consumption.
  • Best Use: Food processing, breweries, HVAC in sensitive areas, and pharmaceuticals.
  • Performance: Higher viscosity (requires more pumping power) and lower efficiency than MEG.
  • Cost: More expensive, often 30% more costly than MEG.

 

Item MEG (Monoethylene Glycol) Propylene Glycol (PG)
CAS Number 107-21-1 57-55-6
Chemical Formula C₂H₆O₂ C₃H₈O₂
Toxicity Toxic if ingested Low toxicity / food-grade available
Main Uses PET, polyester, antifreeze, coolants Food, pharma, cosmetics, HVAC
Coolant Performance Excellent heat transfer Good, but lower than MEG
Regulatory Limits Restricted in food & consumer contact Widely approved (FDA, USP grades)
Cost Lower Higher
Market Volume Very high Medium

 

 

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