what is Ampicillin Sodium for Injection?
Ampicillin is a broad-spectrum, semisynthetic, beta-lactam penicillin antibiotic. It works by inhibiting cell wall synthesis within the bacteria. Ampicillin shows bactericidal activity against a wide range of gram-positive and gram-negative microorganisms, such as E. coli and Klebsiella. At high dosages, this antibiotic is effective against penicillin-sensitive enterococci.
Ampicillin Sodium for Injection is an antibiotic used to treat various types of bacterial infections in both small and large animals. It is indicated for the treatment of urinary tract infections, skin and soft tissue infections, systemic infections like sepsis, and other infections.
The action of Ampicillin Sodium
Ampicillin sodium provides bactericidal activity against a wide range of common Gram-positive and Gram-negative pathogens. Ampicillin's activity occurs during the stage of active multiplication of the pathogen and acts through inhibition of biosynthesis of cell wall mucopeptide. In vivo studies have demonstrated the susceptibility of many strains of the following Gram-positive bacteria: Staphylococcus spp. and Streptococcus spp. (including S. equi). In vivo studies have also demonstrated the susceptibility of many strains of the following Gram-negative bacteria: E. coli and Proteus mirabilis.
Ampicillin Sodium Indications in livestock
1. Swine
Respiratory tract infections: swine pneumonia and bronchitis caused by Bartonella and Streptococcus;
Digestive tract infections: white diarrhea in piglets, bacterial diarrhea, etc;
Genitourinary infections: e.g. cystitis, urinary tract infections;
Postoperative or traumatic infections: to prevent or treat secondary infections after trauma.
2. Cattle
Respiratory tract infections: bovine pneumonia, bronchitis, bovine infectious pleuropneumonia;
Digestive tract infections: diarrhea and necrotizing enteritis in calves caused by E. coli;
Uteritis: uterine infections in cows after delivery or after abortion;
Mastitis: especially caused by staphylococci, streptococci, etc;
Arthritis and osteomyelitis
3. Horses
Respiratory tract infections: pneumonia and bronchitis in horses, respiratory diseases caused by gram-positive and gram-negative bacteria.
Urinary tract infections: e.g. cystitis, urinary tract infections.
Digestive tract infections: for diarrhea caused by bacterial enteritis and E. coli infections.
Traumatic or postoperative infections: for bacterial infections caused by postoperative or trauma.
