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Dimethylformamide (DMF) : The Universal Solvent in The Organic Industry

Jan 13, 2026 Leave a message

CAS 68-12-2 Dimethylformamide (abbreviation DMF), also known as N,N-dimethylformamide, is a dimethyl substitute of formamide, and both methyl groups are located on N (nitrogen) atoms, so it is name. DMF is a colorless and transparent liquid with high boiling point, low freezing point, good chemical and thermal stability, and is miscible with water and most organic solvents.

As an important chemical raw material and excellent solvent, DMF (dimethylformamide) is widely used in polyurethane, acrylic, food additives, medicine, pesticides, dyes, electronics and other industries.

 

Physical & Chemical Properties of Dimethylformamide (DMF)

Boiling Point: 153°C (307°F)

Density: 0.944 g/cm³ @ 20°C

Solubility: Fully miscible with water and most organic solvents

Viscosity: Low viscosity solvent

Flash Point: 58°C (136°F) (Closed Cup)

Evaporation Rate: Low

Vapor Pressure: 3.77 mmHg @ 25°C

Dielectric Constant: 36.7

Polarity: Highly polar aprotic solvent

Biodegradability: Readily biodegradable

 

CAS 68-12-2 NN-Dimethylformamide DMF Our Product Information
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N,N-Dimethylformamide DMF Solvent key applications

1. Solvent: A strong polar solvent used in a variety of chemical reactions and industrial processes.
N,N-Dimethylformamide DMF is a powerful polar aprotic solvent with a high dielectric constant and exceptional solvation ability, enabling it to dissolve a wide range of organic and inorganic compounds.

 

2. Pharmaceuticals: It is used as a solvent for drug formulation and in the production of active pharmaceutical ingredients.
CAS 68-12-2 DMF Dimethylformamide is a critical medium for synthesising and crystallising APIs in pharmaceuticals. Its high purity and stability under rigorous conditions ensure consistent performance in multi-step syntheses and aid the development of controlled-release drug formulations.

 

3. Polymer industry: It is used in the manufacture of polymers such as acrylic fibres.
DMF chemical is the primary industrial solvent used to produce acrylic fibres, as it uniquely dissolves polyacrylonitrile to form spin dope for wet-spinning processes. DMF is also essential for synthesising and processing polyurethanes, polyimides and other high-performance polymers.

 

4. Electronics: It is used in the manufacture of semiconductors and for cleaning electronic components.
Ultra-pure DMF (cas 68 12 2) is used in photoresist stripping, PCB cleaning and as a solvent for polyimide coatings in flexible circuits. Its ability to remove organic residues without leaving traces is vital for semiconductor fabrication and ensuring the reliability of components.

 

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