N,N-Dimethylacetamide (DMAc) is a polar aprotic solvent widely used in drug synthesis, polymer production, and chemical processes. Its molecular formula is CH3CON(CH3)2, its molecular weight is 87.12 g/mol, and its CAS number is 127-19-5. Dimethylacetamide plays an important role in textiles, pharmaceuticals, agriculture, and polymer manufacturing.
DMAC Solvent Dimethylacetamide CAS 127-19-5
Purity, %(wt)：≥99%
CAS Number: 127-19-5
Appearance: Colorless, transparent liquid
Boiling Point: ~165–166°C
Solubility: Miscible with water and most organic solvents
Polarity: Strong polar aprotic solvent
Odor: Slight amine-like smell
DMAC Chemical Formula:
The chemical formula of DMAc (N,N-dimethylacetamide) is C4H7NO. Its structural formula is often written as CH3CON(CH3)2 or C4H9NO, representing an acetamide group in which the nitrogen atom is replaced by two methyl groups.
- The structural formula of dimethylacetamide is shown below:
DMAC Solvent Properties:
| Chemical Name | N,N-Dimethylacetamide |
| Synonyms | DMAc; DMA |
| CAS Number | 127-19-5 |
| Molecular Formula | CH3CON(CH3)2 |
| Molecular Weight | 87.12 g/mol |
| Appearance | Colorless, clear liquid |
| Boiling Point | 165–166 °C |
| Melting Point | -20 °C |
| Density (20°C) | 0.936–0.944 g/cm³ |
| Vapor Pressure (20°C) | ~0.5 kPa |
| Flash Point (Closed Cup) | 63–70 °C |
| Solubility | Completely miscible with water and most organic solvents |
| Polarity | Highly polar aprotic solvent |
| Stability | Stable under normal temperature and pressure |
| Flammability | Combustible liquid |
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CAS 127-19-5 DMAC Solvent Uses
1. Fiber and Polymer Industry
N,N-Dimethylacetamide is widely used in the production of synthetic fibers such as:
- Polyacrylonitrile (PAN)
- Polyurethane (PU)
- Aramid fibers (e.g., Kevlar-type materials)
It acts as a spinning solvent, ensuring uniform fiber formation and high product quality.
2. Coatings and Resins
In coatings and resin formulations, DMAC solvent is used to:
- Dissolve high-performance resins
- Improve film formation
- Enhance coating uniformity
It is commonly found in industrial coatings and synthetic leather production, adhesives.
3. Pharmaceutical Manufacturing
Dimethylacetamide (CAS 127-19-5) plays a critical role in the pharmaceutical industry by:
- Acting as a reaction medium in drug synthesis
- Improving solubility of active pharmaceutical ingredients (APIs)
4. Chemical Synthesis
Due to its stability and polarity, DMAC solvent is frequently used in organic reactions; catalytic processes; intermediate production.
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