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Perchloroethylene (PCE) CAS 127-18-4 : Uses, Properties, And Safety

Nov 26, 2025 Leave a message

CAS 127-18-4 Tetrachloroethylene, also known as perchloroethylene and abbreviations such as perc (or PERC), and PCE, is a chlorocarbon with the formula Cl2C=CCl2. It is a volatile, non-flammable, stable, colorless and dense liquid widely used for dry cleaning of fabrics and as a metal degreasing solvent.

 

Perchloroethylene (PCE) CAS 127-18-4 - Properties

Chemical and Physical Properties

Chemical Formula: C₂Cl₄

Molecular Weight: 165.83 g/mol

Appearance: Colorless liquid

Odor: Sweet, ether-like, pungent

Density: 1.622 g/cm³ (heavier than water)

Boiling Point: 121 °C (250 °F)

Vapor Pressure: 14 mmHg at 25°C (indicates high volatility)

Solubility:

Very low in water: ~150 mg/L at 25°C

Miscible with most organic solvents (alcohols, ethers, oils).

Stability: Stable under normal conditions but can decompose under high heat or light to produce toxic fumes (phosgene, hydrogen chloride).

 

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Perchloroethylene (PCE) CAS 127-18-4 - Uses

1.Tetrachloroethylene (PCE) is widely used, mainly used as metal degreasing solvent, but also used as an insect repellent. Tetrachloroethylene can be used as fat extraction agent, fire extinguishing agent and smoke agent, and can also be used in the synthesis of trichloroethylene and fluorinated organic compounds.

 

2. Perchloroethylene CAS 127-18-4 is widely used as natural and synthetic fiber dry cleaning agent. It is also used as degreasing detergent for metals, general solvent and intermediate for organic synthesis.

 

3. Used as a standard material for chromatographic analysis.

 

4. For adhesive repellent, fat extraction agent, also used in organic synthesis.

 

Perchloroethylene (PCE) CAS 127-18-4 - Safety

1. Toxicity: Perchloroethylene (PCE) is toxic. Long-term exposure to or inhalation of high concentrations of tetrachloroethylene may affect the respiratory system, liver, kidneys, and central nervous system.

 

2. Flammability: Tetrachloroethylene is a flammable liquid, and its vapor can form explosive mixtures. Appropriate fire prevention measures must be taken when storing and handling tetrachloroethylene.

 

3. Environmental Impact: PCE has a certain environmental impact. It can enter the environment through air, water, and soil, and may cause damage to aquatic life and terrestrial ecosystems.

 

4. Exposure Precautions: When using or handling tetrachloroethylene, follow safe operating procedures and avoid direct contact with skin and eyes. Wear appropriate protective equipment, such as gloves, safety glasses, and respiratory protective equipment, if necessary.

 

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