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The Complete Guide To Ethyl Acetate / Ethyl Ethanoate / EtOAc CAS 141-78-6

Mar 25, 2026 Leave a message

CAS 141-78-6 Ethyl ethanoate is another name for ethyl acetate, an ester derived from ethanol and acetic acid. It is asweet-smelling clear liquid which is used as a solvent.Properties of ethyl ethanoate include:

  • Chemical formula: C4H8O2
  • Molecular weight: 88.11 g/mol
  • Appearance: Colourless liquid with a fruity odour
  • Boiling point: 77.1°C
  • Flash point:-4°C (closed cup)
  • Solubility: Limited solubility in water; miscible with most organic solvents
  • Its rapid evaporation and relatively low toxicity make it a valuable solvent across laboratory, industrial,and consumer applications.

 

What are the properties of ethyl acetate/EtOAc?

Understanding the physical and chemical properties of ethyl acetate is crucial for manufacturers across various industries. These key parameters frequently appear in safety data sheets, process engineering calculations, and regulatory documents, making it one of the most frequently cited properties of this solvent.

 

Key Physical and Chemical Properties

Property Value
Appearance Colorless liquid
Odor Fruity, sweet
Boiling Point ~77°C
Density ~0.90 g/cm³
Flash Point -4°C
Solubility Slightly soluble in water
Vapor Pressure High

 

Why Boiling Point Matters

Ethyl acetate / Ethyl Ethanoate has a boiling point of 77.1°C, which is higher than that of low-boiling solvents (such as diethyl ether, 34.6°C), but much lower than that of high-boiling solvents (such as toluene, 110.6°C). This moderate boiling point makes it an excellent fast-evaporating solvent.

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Uses of Ethyl Acetate EtOAc Solvent 

  1. Organic Chemical Ethyl acetate is primarily used as an industrial solvent, widely applied in paints, coatings, adhesives, nail polish remover, cleaning products, printing inks, and perfumes.
  2. In the food and flavor industry, it is naturally found in fruits and wines and is used in artificial fruit flavorings and the flavoring of spirits such as whiskey.
  3. In the pharmaceutical industry, it is used as a solvent for drug purification and for decaffeinating coffee and tea.
  4. In the laboratory, it is a standard solvent for chromatography and extraction.

 

Ethyl acetate liquid has low acute toxicity, with an acceptable daily intake (ADI) of 0–25 mg/kg, but it is flammable and irritating to the eyes, skin, and respiratory system. It should be stored in a cool, well-ventilated place, away from sources of fire and heat.

 

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Handling and Storage Guidelines for Ethyl Ethanoate

CAS 141-78-6 Ethyl Ethanoate has a wide range of uses, but due to its flammability and potential health hazards, it requires careful handling.

  • Keep away from oxidizers, heat sources, open flames, and all sources of ignition.
  • Store in a well-ventilated place, avoiding vapor buildup.
  • Store in its original, tightly closed container, maintaining a temperature between 15°C and 25°C.
  • Avoid direct sunlight, high temperatures, and humidity.
  • Store separately from oxidizers and incompatible substances.
  • Ensure storage temperature is above its freezing point.
  • Store securely to prevent spills.

 

Always consult the Safety Data Sheet (MSDS) before use and storage. Contact us for more information.

 

 

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