What Do You Know about Tylosin Injection?
Tylosin is a macrolide antibiotic that was obtained in the United States in 1959 from cultures of Streptomyces tradescens. Telocin is a white flaky crystal, slightly soluble in water and alkaline. The products are tartrate, phosphate, hydrochloride, sulfate and lactate, which are soluble in water. Its aqueous solution can be stored for 3 months at 25°C and pH 5.5-7.5, but will fail if the aqueous solution contains metal ions such as iron and copper.
How tylosin works?
Tylosin tartrate inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome of bacteria, thus preventing bacterial growth and reproduction, and finally achieving the effect of bacterial inhibition. Because Tylenol has significant antibacterial activity against Mycoplasma, it is commonly used in the treatment of pneumonia and arthritis caused by Mycoplasma.
What diseases is Tylosin injection used to treat?
Clinically, tylosin is used to treat and prevent infections caused by a wide range of pathogenic bacteria, including Mycoplasma, Staphylococcus aureus and Bartonella. These infections involve various aspects of the respiratory, intestinal, reproductive and locomotor systems. For example, it is effective in treating chronic respiratory diseases, avian air sacculitis, oviductitis, and Mycoplasma synoviae infections in poultry. In addition, the drug can be used in poultry farm injections and egg dipping to help purify Mycoplasma, which is effective in preventing and controlling Mycoplasma secondary infections during outbreaks of viral diseases in livestock and poultry.
Advantages of Tylosin
1. Significant anti-mycoplasma effect
Tylosin injection has strong inhibitory effect on many kinds of mycoplasma such as Mycoplasma pleuropneumoniae, and it is the first choice drug for treating Mycoplasma pneumoniae infectious diseases.
2. Broader antibacterial spectrum
It mainly has strong inhibitory effect on various gram-positive bacteria, also has inhibitory effect on some gram-negative bacteria, campylobacter, spirochetes, and has anti-coccidial effect.
3.Rapid absorption and excretion
Tylosin injection can reach the effective inhibitory concentration in a short time, and maintain a certain time, either orally or by injection, the drug is rapidly excreted from the body after it stops, and there is almost no residue in the tissues.
4. Good diffusion ability
It can penetrate all organs, tissues and body fluids, especially through the plasma membrane, blood-brain, blood-eye and blood-testis barriers, which makes Tylosin l have a wide range of clinical applications.