Products Description
NAME: Acetonitrile (ACN)
Synonyms: Cyanomethane / Methyl cyanide (MeCN) / Ethanenitrile / Ethyl nitrile / Methanecarbonitrile
Molecular Formula: C2H3N
Molecular Weight: 41.052
CAS NO.: 75-05-8
Density: 0.7±0.1 g/cm3
Boiling point: 81-82 ºC
melting point: −45 °C
flashing point: 2 ºC
Appearance: Colorless clear liquid.
Solubility: It is miscible with water and various organic solvents.

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| Item | Specification | Result |
| Appearance | Colorless Liquid | Colorless Liquid |
| Molar Refractive Index | 11.22 | 11.22 |
| Molar volume (cm3/mol) | 54.9 | 54.9 |
| Isotonic specific volume (90.2K) | 120.0 | 120.0 |
| Surface tension (dyne/cm) | 22.7 | 22.7 |
| Polarizability (10-24cm3) | 4.45 | 4.45 |
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CAS 75-05-8 Applications:
High-Performance Liquid Chromatography (HPLC):
Acetonitrile ACN is one of the most commonly used organic modifiers in HPLC mobile phases due to its low UV absorbance, low viscosity, and ability to elute a wide range of compounds. It provides excellent resolution and sensitivity in analytical separations.
Pharmaceutical Manufacturing:
Methyl Cyanide is extensively used as a solvent in the synthesis, purification, and formulation of various pharmaceutical active ingredients (APIs) and intermediates. Its ability to dissolve both polar and nonpolar compounds makes it highly versatile.
DNA and Peptide Synthesis:
ACN serves as a crucial solvent in oligonucleotide and peptide synthesis, facilitating coupling reactions and purification steps.
Extraction Solvent:
Cyanomethane CAS 75-05-8 is employed as an extraction solvent for fats, oils, and other organic compounds from various matrices in the food, environmental, and pharmaceutical industries.
Chemical Synthesis:
ACN Solvent is a versatile reaction medium for a wide variety of organic reactions, including nucleophilic substitutions, Diels-Alder reactions, and transition metal-catalyzed reactions. It can also act as a nitrile source in some transformations.
Safety Protection:
Keep away from fire, heat sources, flammable and combustible materials, and avoid direct sunlight. Avoid mixed storage and transportation with oxidants, reducing agents, acids, and alkalis. The warehouse temperature should not exceed 30℃.
Why choose GNEE BIO?
GNEE BIO has earned trust as a leading China chemical manufacturer by delivering precision, consistency, and compliance.
✅ GMP & ISO 9001 Certified – Quality you can trust
✅ REACH Compliant – Safe and sustainable
✅ Global Distribution – Fast, secure delivery worldwide
Packaging
Customizable labels and packaging; OEM / ODM service

Company Profile
GNEE BIO is located in Henan Province, China. We are a new chemical enterprise integrating R&D, production and supply of professional chemicals. Since its founding, we have established long-term, stable business relationships with over 300 companies across a wide range of sectors, including coatings, papermaking, chemical production, rubber, and plastics.
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Our best-selling products include: Dichloromethane; Acetic acid; Methyl Sulfoxide; Methyl Sulfoxide DMSO (Industrial and pharmaceutical grade); Ethylene Glycol; Isopropanol; 1-Propanol; p-Xylene, etc.



FAQ
Q1:Can I get some samples?
A: Yes, we can supply the free sample,but the shipping cost be paid by our customers.
Q2:How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T,Western Union or Paypal or secure payment.
Q3:How to confirm the Product quality before place orders?
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q4:What's your MOQ?
A: Our MOQ is 1 ton.
Q5: How about delivery lead time?
A: Delivery lead time: About 7-10 days after payment confirmed.(Chinese holiday not included).
Q6:Is there a discount?
A: Different quantity has different discount.
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