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What is dichloromethane DCM (CAS 75-09-2) used for in chemistry?

Mar 19, 2026 Leave a message

CAS No 75-09-2 Dichloromethane (DCM), also known as methylene chloride, is a volatile, non-flammable organic solvent widely used in chemical synthesis due to its ability to dissolve a broad range of organic compounds, low boiling point, and stability.

 

Dichloromethane (DCM) Specifications Table

PropertyDetails
CAS Number75-09-2
Chemical NameMethylene Chloride (Dichloromethane)
Molecular FormulaCH2Cl2
AppearanceClear, colorless liquid
Odor> Pleasant, mild, ether-like
Molecular Weight84.93 g/mol
Boiling Point39.6–40.0 °C
Melting Point−96.7 °C
Density (20 °C)1.325–1.330 g/cm³
Refractive Index (20 °C1.4240–1.4250
Vapor Pressure (20 °C)~350–390 mmHg
Flash PointNon-flammable
Water Solubility (20 °C).3 g/L (sparingly soluble)
Purity (%)≥99.8 %
Main ImpuritiesMethanol, chloromethane, trichloromethane
Typical ColorASTM ≤2.0

 

 

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What is dichloromethane DCM (CAS 75-09-2) used for in chemistry?

1. Organic Reaction Solvent

Dichloromethane (DCM) is commonly used as a reaction medium in organic synthesis. It can dissolve a wide variety of organic compounds and is chemically stable under various reaction conditions.

Applications:

  • Pharmaceutical intermediate synthesis
  • Polymer chemistry
  • Fine chemical production

 

2. Extraction Solvent (Liquid-Liquid Extraction)

One of the most important uses of methylene chloride (DCM) is liquid-liquid extraction. Because it is insoluble in water and has a higher density than water (forming a bottom layer), it is ideal for extracting organic compounds.

Applications:

  • Alkaloid extraction
  • Natural product separation
  • Active drug purification

 

3. Paint Removal and Cleaning (Industrial Chemistry)

Beyond laboratory chemistry, dichloromethane is also widely used in:

  • Paint strippers
  • Adhesive removers
  • Metal degreasing

This is because dichloromethane chemical has a strong dissolving ability for resins, oils, and coatings.

 

4. Pharmaceutical Applications

In the pharmaceutical industry, dichloromethane (CAS 75-09-2) is used for drug extraction, processing of active pharmaceutical ingredients and intermediates, and as a solvent in synthetic reactions.

 

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People Also Ask:

Why is dichloromethane a good solvent for extraction?

CAS 75-09-2 Dichloromethane (DCM), also known as methylene chloride, is a good solvent for extraction processes due to its unique properties. It is a polar, aprotic solvent, which means it has a significant dipole moment but does not have any hydrogen atoms that can participate in hydrogen bonding. This allows DCM to dissolve a wide range of polar and nonpolar compounds, making it very versatile in extraction processes.

 

What kind of solvent is DCM?

Dichloromethane (DCM), also commonly known as methylene chloride, is a polar, aprotic, chlorinated organic solvent. It is a colorless, highly volatile liquid with a sweet, chloroform-like odor.

 

What is a good substitute for DCM?

Ethyl acetate, acetonitrile, and toluene are reasonable alternative solvents to consider for reactions that typically employ DCM.

 

 

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