Acetonitrile ACN is dangerous. CAS 75-05-8 Acetonitrile is highly toxic to humans and can be fatal if inhaled, ingested, or absorbed through the skin. It is considered a toxic organic solvent because the body can metabolize acetonitrile into cyanide compounds.
However, when handled properly and with appropriate safety precautions, acetonitrile can be used safely.
Toxicity of Acetonitrile
- Mechanism: Metabolized in the liver to hydrogen cyanide, causing cellular hypoxia similar to cyanide poisoning.
- Exposure Routes: Rapidly absorbed via skin, inhalation, and ingestion.
- Symptoms: Delayed onset (2–12 hours): chest pain, cyanosis, nausea, vomiting, confusion, convulsions, coma.
- Long-term Effects: Chronic exposure may cause thyroid enlargement and kidney/liver damage.
- Acute Toxicity: Acute Toxicity Category 4 – harmful if swallowed or in contact with skin.
Safety
| Category | Information |
|---|---|
| Chemical Type | Polar aprotic solvent |
| Hazard Type | Flammable and toxic solvent |
| Common Applications | Chromatography, synthesis, extraction |
| Safety Requirement | Ventilation and PPE |
Safety Measures:
Personal Protective Equipment (PPE): Wear chemical-resistant gloves (nitrile recommended, but check for breathability), safety goggles or a face shield, and a lab coat to avoid skin and eye contact.
Handling and Storage:
- Keep away from ignition sources: No smoking, open flames, or sparks; use explosion-proof tools.
- Grounding/Earthing: All containers and equipment must be grounded to prevent static discharge.
- Storage Conditions: Store in a cool, dry, well-ventilated area away from strong oxidizers, acids, and alkalis.
- Avoid High Temperatures: Keep containers tightly sealed and away from hot surfaces.
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High-Purity Acetonitrile Solvent Supplier
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As a leading manufacturer and exporter of fine chemicals, Henan Gneebio provides high-quality industrial chemicals. We supply to customers across the chemical, pharmaceutical, and materials industries, ensuring consistent quality, reliable logistics, and professional technical support.
Our chemical products hold international certifications (REACH, ISO, FMQS, HALAL) for global quality recognitio. We have warehouses in coreports such as Qingdao, Tianiin, and Shanghai, with a 15-day express delivery service.
Other Hot-Selling Products
CAS 64-19-7 Acetic acid/Glacial Acetic Acid; CAS 67-68-5 Dimethyl Sulfoxide (DMSO); CAS 67-63-0 Isopropyl alcohol (IPA); CAS 95-47-6 o-Xylene; CAS 106-42-3 p-Xylene; CAS 75-09-2 Dichloromethane (DCM).
Gneebio Product Packaging
| Packaging Type | Net Weight |
|---|---|
| Steel Drum | 160 kg |
| ISO Tank | 20–22 MT |
| IBC Tank | 800–1000 kg |
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