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Is acetonitrile flammable? Is acetonitrile a safe solvent?

Mar 05, 2026 Leave a message

Acetonitrile (CAS 75-05-8) is a highly flammable colorless liquid that ignites readily upon contact with sparks or open flames, with a flash point of only 5.5°C. It is generally not considered a safe solvent due to its toxicity, posing hazards if swallowed, inhaled, or absorbed through the skin.

 

Is acetonitrile solvent (CAS 75-05-8) flammable?

Yes, acetonitrile (CAS 75-05-8) is highly flammable and poses a dangerous fire hazard. It has a low flash point of 2°C (35.6°F). It is categorized as a Class 3 flammable liquid under many chemical safety regulations.
 

Key flammability data:

Property Value
Flash Point ~2°C
Autoignition Temperature ~524°C
Flammable Limits in Air 4.4% – 16%
Physical State Colorless liquid

 

 

Is acetonitrile a safe solvent?

Acetonitrile CAS 75-05-8 is an organic solvent characterized by its non-flammability and low toxicity. It is not considered safe without strict, specialized handling, as it is toxic and can be fatal.

 

Typical safety precautions include:

Personal Protective Equipment:

  • Gloves: Wear chemical-resistant gloves (butyl rubber, Silver Shield/4H®, fluorocarbon rubber/butyl). Nitrile rubber is not recommended.
  • Eyes: Use chemical splash-resistant goggles or a face shield.
  • Body: Wear a lab coat; add an apron if necessary.

Handling Precautions:

  • Highly flammable-Keep away from heat, sparks, and open flames. No smoking.
  • Ground containers and use non-sparking tools to prevent static discharge.
  • Wash hands after use; no eating, drinking, or smoking in work area.
  • Storage Requirements: Store containers tightly closed in a cool, dry, well-ventilated area (flammable cabinet). Keep away from oxidizers, acids, and alkalis.

 

 

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