What Is Dimethylacetamide (CAS 127-19-5)?
N,N-Dimethylacetamide DMAC (CAS 127-19-5) is a high-boiling-point polar aprotic solvent widely used in the chemical, pharmaceutical, and polymer industries. Its high dielectric constant, low volatility, and strong solubility for both polar and nonpolar compounds make it an ideal solvent for high-temperature reactions and polymer synthesis.
DMAC solvent is compatible with a wide range of organic and inorganic compounds, making it an ideal solvent for polyacrylonitrile spinning, polyurethane coatings, and photoresist formulations. Even under harsh reaction conditions, DMAc remains stable, thereby improving process efficiency and product purity.

What are the properties of DMAC solvent?
Basic Physical Properties:
- Chemical formula: C₄H₉NO
- Molecular weight: ~87.12 g/mol
- Appearance: Colorless to slightly yellow liquid
- Odor: Faint amine-like odor
- Density: ~0.94 g/cm³ (at 20°C)
Boiling Point of dimethylacetamide DMAC solvent:
Boiling point: ~165–166°C (329–331°F)
This high boiling point makes DMAc solvent especially suitable for:
- High-temperature chemical reactions
- Polymer processing (e.g., polyimides, polyurethane)
- Industrial applications requiring low evaporation loss
Physical and chemical properties:
| Properties | |
|---|---|
| Molecular Weight | 87.12 |
| Boiling Point (°C at 760 mmHg) | 165.5 |
| Freezing Point (°C) | -20 |
| Density (at 15.6 °C) | 0.9448 |
| Heat of Vaporization | 10.36 kcal/gr.mole |
| Heat of Combustion | 608 kcal/gr.mole |
| Flash Point (°C) | 490 |
| Heat of Formation (Liquid, 0.87 °C) | 0.485 cal/gr. °C |
| Combustion Limits |
Minimum: 2% by volume Maximum: 11.5% by volume |
| Solubility | Fully miscible with water, ether, esters, ketones, and aromatic compounds |
| Hydrolysis Tendency | Tends to hydrolyze in aqueous solutions at high temperatures |
What is Dimethylacetamide DMAc Solvent used for?
1. Pharmaceutical Industry
Dimethylacetamide CAS 127-19-5 is used as a reaction solvent in drug synthesis
Helps in producing active pharmaceutical ingredients (APIs)
2. Polymer and Plastic Industry
Dissolves polymers such as polyacrylonitrile (PAN) and polyurethane
Used in manufacturing synthetic fibers (e.g., acrylic fibers)
3. Chemical Synthesis
DMAC liquid serves as a reaction medium for organic synthesis
Helps improve reaction efficiency due to its polar nature
Used in catalytic and coupling reactions
4. Textile Industry
DMAC CAS 127-19-5 is used in fiber spinning processes
Helps form high-strength synthetic fibers
Improves polymer processing performance
5. Coatings and Adhesives
Dimethylacetamide CAS 127-19-5 acts as a solvent for resins, inks, and adhesives
Enhances coating uniformity and adhesion properties
6. Electronics Industry
Used in the production of high-performance insulating materials
Helps in cleaning and processing electronic components
Dimethylacetamide Solvent CAS 127-19-5
about us
As a leading manufacturer and exporter of chemical solvent, TIANJIN GNEE BIOTECH CO., LTD. provides high-quality industrial chemicals. We supply to customers across the chemical, pharmaceutical, and materials industries, ensuring consistent quality, reliable logistics, and professional technical support.
Our chemical products hold international certifications (REACH, ISO, FMQS, HALAL) for global quality recognitio. We have warehouses in coreports such as Qingdao, Tianiin, and Shanghai, with a 15-day express delivery service.
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Gneebio Product Packaging
| Packaging Type | Net Weight |
|---|---|
| Steel Drum | 250 kg |
| IBC Tank | 1250 kg |
| ISO Tank | Bulk shipment |

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