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What does (CAS 75-05-8) acetonitrile do as a solvent?

Dec 16, 2025 Leave a message

CAS No.: 75-05-8
EC No.: 200-835-2
EC / List name: Acetonitrile

Acetonitrile, also called methyl cyanide, is the simplest organic nitrile, miscible with water, methanol, methyl acetate, ethyl acetate, acetone, ether, acetamide solutions, chloroform, carbon tetrachloride, ethylene chloride and many unsaturated hydrocarbons. Immiscible with many saturated hydrocarbons (petroleum fractions).

 

What does (CAS 75-05-8) acetonitrile do as a solvent?

Acetonitrile CAS 75-05-8 is mainly used as a solvent for purifying butadiene in refineries. It is widely used in barrier applications because of its relatively high dielectric constant and ability to dissolve electrolytes. For similar reasons, it is a popular solvent in cyclic voltammetry.
Its low viscosity and low chemical reactivity also make it a popular choice for liquid chromatography.

 

Acetonitrile plays a significant role as the dominant solvent in the production of DNA oligonucleotides from monomers.
Industrially, it is also used as a solvent in the production of pharmaceuticals and photographic film.

 

In organic synthesis
Acetonitrile is a common two-carbon building block in the synthesis of many useful chemicals, including acetophenone, thiamine, acetamidine and caprylic acid. Its reaction with cyanogen chloride affords malononitrile.

 

 

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Acetonitrile Chemicals

 

Organic Solvent Acetonitrile (ACN)

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