Is acetone (cas 67 64 1) the same as acetonitrile (cas 75 05 8)?
No, acetone and acetonitrile are not the same; they are different organic solvents.
| Property | Acetone (CH₃COCH₃) | Acetonitrile (CH₃CN) |
|---|---|---|
| Structure | Ketone | Nitrile (cyanide) |
| Type | Polar aprotic solvent | Polar aprotic solvent |
| Key Difference | Highly volatile, excellent degreaser. Metabolized normally in the body. | Metabolized to cyanide (toxic). Superior HPLC solvent. |
| Primary Use | Cleaning agent, nail polish remover, solvent in paints/lacquers. | HPLC mobile phase, specialized reaction solvent in synthesis. |
| Odor | Sweet, fruity, "nail polish remover" smell. | Ether-like, milder, sometimes described as "aromatic". |
| Miscibility | Miscible with water. | Miscible with water. |
Similarities:
- Both are polar organic solvents, miscible with water.
- Both are used in liquid chromatography (HPLC) as mobile phases.
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