What is diethyl malonate liquid (CAS 105-53-3) used for?
Diethyl malonate (CAS 105-53-3 ) is a colorless and transparent liquid with the aromatic odor of ether, and the industrial product is a light yellow transparent liquid, which is slightly soluble in water and easily soluble in organic solvents such as alcohol, ether, chloroform and benzene. Since the -H on the active methylene group in the diethyl malonate molecule is easily substituted by other groups, various substitution reactions can be carried out, such as alkylation, acylation, hydroxyalkylation and amide. chemical reaction, etc.
Application of Diethyl malonate
1. Intermediate of organic synthesis, for the preparation of 2-amino-4, 6- dimethoxy-pyrimidine. Diethyl malonate is also used as a plasticizer for cellulose nitrate;
2. Diethyl malonate liquid is widely used in the production of dyes, fragrances, sulfonylurea herbicides; is mainly used in the production of Propylene glycol ethoxymethylenemalonate, barbituric acid, alkyl diethyl malonate, then for the synthesis of pharmaceuticals, such as norfloxacin, lomefloxacin, chloroquine, phenylbutazone, etc., and synthetic dyes and pigments such as benzimidazolone type of organic pigments;
3. As the for intermediates of drugs such as chloroquine, phenylbutazone, sulfadoxine-pyrimethamine and barbiturate;
4. Diethyl Malonate 99% is used as food flavor. Mainly used for the preparation of pear, apple, grape, cherry and other fruit flavors;
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