CAS 67-68-5 Dimethyl Sulfoxide (DMSO) is a versatile organic sulfur solvent with unique chemical properties-including high polarity, excellent solubility, and exceptional skin permeability-that make it a valuable tool in modern medicine.
Dimethyl sulfoxide (DMSO) is a highly versatile organic solvent widely used in both clinical medicine and biomedical research. Known for its exceptional ability to penetrate biological membranes, DMSO has unique therapeutic and pharmaceutical applications. This article explores the medical uses of DMSO, its benefits, and safety considerations.
Key Properties of dMSO
| Chemical Name | DMSO/Dimethyl Sulfoxide/Methyl sulfoxide |
| Molecular Formula | C₂H₆OS |
| Molecular Weight | 78.13 g/mol |
| CAS Number | 67-68-5 |
| Appearance | Colorless, transparent liquid |
| Odor | Slight sulfur-like odor |
| Purity (Typical) | ≥ 99.9% |
| Density (20°C) | 1.095 g/cm³ |
| Boiling Point | 189°C |
| Melting Point | 18.5°C |
| Flash Point | 87°C (Closed cup) |
| Refractive Index (20°C) | 1.479 |
| Viscosity (20°C) | 1.99 mPa·s |
| Solubility | Miscible with water and most organic solvents |
medical uses of DMSO solvent
1. FDA-Approved Medical Uses of DMSO
The most established medical use of DMSO is in the treatment of interstitial cystitis (IC). DMSO has been approved in several countries, including the United States, for the treatment of interstitial cystitis, a chronic bladder disease characterized by pain, inflammation, and urinary frequency.
2. Anti-inflammatory and Analgesic Applications
DMSO possesses potent anti-inflammatory and analgesic properties, thus it can be used for certain off-label or experimental treatments, such as arthritis and joint inflammation, musculoskeletal injuries, and soft tissue swelling.
3. Drug Delivery Enhancer
One of the most unique medical properties of DMSO solvent is its ability to penetrate the skin and carry small molecule drugs. It can be used as a penetration enhancer in topical formulations via transdermal administration, promoting drug absorption through the skin into the systemic circulation.
Note: Because dimethyl sulfoxide (DMSO) may also carry harmful substances into the body, caution should be exercised when using it!
Dimethyl sulfoxide DMSO Organic Solvent
Benefits of Dimethyl Sulfoxide (DMSO)
1. Anti-inflammatory
Helps reduce swelling and inflammation, especially in joints and tissues.
2. Pain Relief
Has a mild analgesic effect, helping to relieve muscle and joint pain.
3. Promotes Drug Absorption
Easily penetrates the skin, helping medications enter the body.
4. Cell Protection (Cryopreservation)
Protects cells during the freezing process; widely used for storing stem cells and blood cells.
5. Antioxidant
Neutralizes free radicals, helping to protect cells from damage.
6. Improves Blood Circulation
May promote blood circulation, accelerating healing.
Side Effects and Precautions
Medical-grade DMSO is generally well-tolerated when used as directed by a physician, but the following side effects may still occur:
- Intravesical use (for interstitial cystitis): Pain or burning sensation during instillation, temporary garlic-like odor on breath or skin (a common metabolite of DMSO), and occasional urinary frequency or urgency.
- Topical use: High concentrations may cause skin irritation and contact urticaria.
Precautions: DMSO is contraindicated in pregnant or breastfeeding women, those allergic to DMSO, and those taking anticoagulants. Furthermore, avoid application to broken or irritated skin to prevent increased absorption and potential toxicity.
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Gneebio Product Packaging
| Packaging Type | Net Weight |
|---|---|
| Steel Drum | 250 kg |
| IBC Tank | 1250 kg |
| ISO Tank | Bulk shipment |
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