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What Is HPLC Grade Acetonitrile Used For?

Jan 29, 2026 Leave a message

What Is HPLC Grade Acetonitrile?

HPLC grade Acetonitrile ACN is a premium solvent with a purity level of at least 99.9% and ultra-low UV absorbance. It is the go-to choice for High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS) mobile phases, delivering low background noise, minimal impurities and high detection sensitivity for complex mixture analysis across multiple fields.

 

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What Is HPLC Grade Acetonitrile Used For?

Acetonitrile (ACN) of HPLC grade is versatile for analytical and lab operations, with key uses spanning various professional areas:

  • HPLC/UHPLC Mobile Phase: It excels in reverse-phase chromatography, boasting low viscosity, a 190-200 nm UV cutoff and strong elution power, which boosts separation resolution.
  • LC-MS Analysis: Its high purity and volatility eliminates spectral interference, making it perfect for mass spectrometry analysis.
  • Extraction: It is a reliable solvent for extracting, dissolving and purifying different organic compounds in sample preprocessing.
  • Quality Control: It is a critical reagent for testing the purity of APIs in quality checks.
  • Environmental Analysis: It is applied to detect various contaminants in water and soil samples for environmental monitoring.
  • Organic Synthesis: It is a basic solvent for research and synthesis experiments.

 

 

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As a leading manufacturer and exporter of fine chemicals, Henan Gneebio provides high-quality industrial chemicals. We supply to customers across the chemical, pharmaceutical, and materials industries, ensuring consistent quality, reliable logistics, and professional technical support.

Our chemical products hold international certifications (REACH, ISO, FMQS, HALAL) for global quality recognitio. We have warehouses in coreports such as Qingdao, Tianiin, and Shanghai, with a 15-day express delivery service.

 

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