What is Sulfadiazine and Trimethoprim Suspension used for?
What is Sulfadiazine and Trimethoprim Suspension
It is an antimicrobial drug widely used in livestock and poultry and consists of two main active ingredients: sulfadiazine and methotrexate. This drug is widely used in animal husbandry for the treatment of infectious diseases caused by a wide range of bacteria, especially bacterial infections of the respiratory, digestive and urinary tracts.
How Sulfadiazine and Trimethoprim Suspension works
Sulfasalazine is a drug that inhibits the bacterial enzyme dihydrofolate synthase, which prevents the first step in the synthesis of folic acid and inhibits bacterial growth.
Trimethoprim, on the other hand, enhances the antimicrobial effect of sulfasalazine by inhibiting the enzyme dihydrofolate reductase, which further blocks the production of folic acid.
This double blockage of folate metabolism prevents the bacteria from synthesizing the required nucleic acids and proteins, ultimately leading to bacterial death. This combination is particularly suitable for combating a wide range of infections caused by Gram-positive and Gram-negative bacteria.

What is Sulfadiazine and Trimethoprim Suspension used for?
It's used to treat or prevent bacterial infections, such as:
1.Acute Equine Glandular Disease: an infectious disease caused by streptococcus, manifested by fever and swollen lymph nodes.
Respiratory Tract Infections: Effective against a wide range of respiratory bacterial infections in cattle, swine and poultry, relieves coughing and dyspnea.
2.Acute genitourinary tract infections: It is suitable for treating symptoms such as frequent urination and painful urination, and can quickly control the infection.
3.Traumatic Infections: Prevents open wound infections and promotes healing by inhibiting bacterial growth.
4.Abscess: Helps to remove pus, relieve pain and swelling, and prevent the spread of infection.
5.Uterine infections: Effectively treat endometritis and promote the restoration of the reproductive system to health.
6.Bacterial dysentery: for watery diarrhea in young animals such as piglets and lambs, rapidly controlling the propagation of germs.
Side Effects
As with all pharmaceuticals, some unwanted effects can occur from the use of Sulfadiazine + Trimethoprim Oral Solution.
Serious side effects may include:
allergic reaction, including anaphylaxis
urine crystals
central nervous toxicity
liver damage
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