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What is Tetrahydrofuran (THF CAS 109-99-9) used for?

Nov 25, 2025 Leave a message

What is Tetrahydrofuran THF (CAS 109-99-9)?

CAS 109-99-9 Tetrahydrofuran (THF), or oxolane, is an organic compound with the formula (CH2)4O. The compound is classified as heterocyclic compound, specifically a cyclic ether. It is a colorless, water-miscible organic liquid with low viscosity. It is mainly used as a precursor to polymers. Being polar and having a wide liquid range, THF (CAS 109-99-9) is a versatile solvent. It is an isomer of another solvent, butanone.

 

What Are The Properties Of Tetrahydrofuran (CAS 109-99-9)?

Property Description
Chemical Formula C₄H₈O
Appearance Clear, colorless liquid
Odor Ether-like, pungent, and sweet
Boiling Point 66 °C (151 °F)
Melting Point -108 °C (-162 °F)
Density 0.8892 g/cm³ at 20 °C
Vapor Pressure 132 mmHg at 20 °C (indicates high volatility)
Solubility Miscible with water and most common organic solvents.
Flash Point -14 °C (7 °F) - Highly Flammable
Auto-ignition Temp. 321 °C (610 °F)

 

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What is Tetrahydrofuran (THF CAS 109-99-9) used for?

As a Reaction Solvent: Its ability to dissolve polar and non-polar compounds makes it a preferred solvent for Grignard reactions, polymerizations, and hydride reductions.

 

Polymer Industry: Tetrahydrofuran (CAS 109-99-9) is the primary solvent for polyvinyl chloride (PVC) cements and is used in the production of polytetramethylene ether glycol (PTMEG).

 

Chemical Synthesis: THF is a key starting material and solvent in the synthesis of pharmaceuticals, agrochemicals, and dyes.

 

Laboratory Use: Commonly used in laboratory chromatography as a component of mobile phases, and for extraction and purification processes.

 

Adhesives and Coatings: THF is used as a solvent for natural and synthetic resins.

 

where to Buy Tetrahydrofuran THF?

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Henan Gneebio was established in 2016, adhering to thecorporate philosophy of "global chemical raw material supplier" and focusing on high-quality chemical industries. The company primarily deals chemical raw materials, such as dichloromethane; methyl sulfoxide DMSO (industrial and pharmaceutical grade); ethylene glycol (MEG); p-Xylene, etc.

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Tetrahydrofuran 99.9% Thf

Packaging 

 

Package

Quantity/20'FCL

160KGS Drum

12.8MTS

800KGS IBC Drum

16MTS

IOS Tank

18.5MTS

 

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