What is the CAS number of 75-05-8?
The CAS number 75-05-8 is Acetonitrile. Also known as methyl cyanide, cyanomethane, abbreviated as ACN.
Acetonitrile ACN is the simplest organic nitrile, it is a colorless and transparent liquid at room temperature. It is highly volatile and has a special Chemicalbook smell similar to ether. It is flammable and burns when burned. Accompanied by bright flames. Miscible with water, methanol, carbon tetrachloride, methyl acetate, ethyl acetate, dichloroethane and many unsaturated hydrocarbon solvents.
CAS number: 75-05-8
Structure:
What is (CAS number 75-05-8) Acetonitrile Used for?
HPLC:
Acetonitrile ACN is a popular organic modifier in HPLC mobile phases due to its low UV absorption, low viscosity, and ability to elute a wide range of compounds. It provides excellent resolution and sensitivity in analytical separations.
Pharmaceutical Manufacturing:
CAS 75-05-8 Acetonitrile is used extensively in the synthesis, purification, and formulation of various APIs and intermediates. Its ability to dissolve both polar and non-polar compounds makes it highly versatile.
DNA and Peptide Synthesis:
ACN is a crucial solvent in oligonucleotide and peptide synthesis, facilitating coupling reactions and purification steps.
Extraction Solvent:
Acetonitrile Acn is employed as an extraction solvent for fats, oils, and other organic compounds from various matrices in the food, environmental, and pharmaceutical industries.
Chemical Synthesis:
It is a versatile reaction medium for a wide variety of organic reactions, including nucleophilic substitutions, Diels-Alder reactions, and transition metal-catalysed reactions. It can also act as a nitrile source in some transformations.
Spectroscopy:
ACN CAS 75-05-8 is often used as a solvent in UV-Vis, IR, and NMR spectroscopy due to its relatively simple structure and spectral properties.
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