The density of acetonitrile (CAS 75-05-8) is approximately 0.786 g/mL at 25 °C (or 0.782-0.783 g/mL at 20 °C).
Acetonitrile (CAS 75-05-8) is it a colorless, volatile liquid less dense than water. Synonyms include Cyanomethane and Methyl cyanide. It is widely used as a polar aprotic solvent in HPLC, organic synthesis, and pharmaceutical manufacturing. Temperature significantly affects the density of acetonitrile; as temperature increases, density decreases, and as temperature decreases, density increases. Density is inversely proportional to temperature.
- 5°C:~ 0.823 g/mL
- 15°C:~ 0.812 g/mL
- 20°C:~ 0.807 g/mL
- 35°C:~ 0.790 g/mL
Compared to Water
| Substance | Density (20°C) | Relative Density vs Water |
|---|---|---|
| Acetonitrile | 0.786 g/cm³ | Lighter than water |
| Water | 1.000 g/cm³ | Reference |
What is the function of acetonitrile density?
As a polar, non-protonic solvent with low viscosity and high water solubility, the density value of acetonitrile (CAS 75-05-8) holds critical significance for precision laboratories and industrial processes.
- Used to calculate mass values during the preparation of mobile phases for liquid chromatography.
- Critical for calculating mass flow rates during the extraction of butadiene and other hydrocarbons.
- Applied to precisely calculate the mass of chemical cargo and adjust measured volumes based on temperature.
Does the density of acetonitrile affect its storage?
Acetonitrile has low density (0.787 g/cm³) (floats on water) and high volatility, which determine its storage and safety rules.
- Vapors are 1.42× heavier than air, can accumulate in low areas and pose fire risks.
- Keep cool (below 23°C), away from heat, sunlight, and ignition sources.
- Store in well-ventilated, fireproof areas.
- Keep containers tightly closed to avoid vapor release.
- Class IB Flammable Liquid; low flash point (5.5°C) requires strict fire prevention.
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