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What is the difference between DMA cand DMF solvent?

Apr 28, 2026 Leave a message

DMF (N,N-Dimethylformamide) and DMAC (N,N-Dimethylacetamide) are common organic solvents that are widely used in the chemical, pharmaceutical, electronics and fiber industries. Their main differences are as follows:

 

What Is Dimethylacetamide (CAS 127-19-5)?

 

Feature DMAc (DMA) DMF
Full name N,N-Dimethylacetamide N,N-Dimethylformamide
CAS number 127-19-5 68-12-2
Chemical group Amide (acetamide) Amide (formamide)
Boiling point ~165–166°C ~153°C
Odor Mild, less pungent Strong fishy/ammonia-like
Solvent strength Slightly milder Stronger solvent power
Stability More thermally stable Slightly less stable at high heat
Common use Fibers, PU, coatings, membranes Resins, pharmaceuticals, acrylics

 

Chemical structure difference:

N,N-Dimethylacetamide DMAc (DMA) has an acetamide group (CH₃CON(CH₃)₂).
N,N-Dimethylformamide DMF has a formamide group (HCON(CH₃)₂).

 

Industrial application differences

N,N-Dimethylformamide DMF solvent: Used in the wet spinning of polyacrylonitrile fibers, as a solvent for acrylic plastics, and in peptide coupling reactions in pharmaceutical production.

 

N,N-Dimethylacetamide DMAc solvent: A preferred solvent for dissolving certain polymers, such as polyurethane. Due to its stability, it is commonly used in the production of synthetic fibers and films.

 

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As a leading manufacturer and exporter of chemical solvent, TIANJIN GNEE BIOTECH CO., LTD. provides high-quality industrial chemicals. We supply to customers across the chemical, pharmaceutical, and materials industries, ensuring consistent quality, reliable logistics, and professional technical support.

Our chemical products hold international certifications (REACH, ISO, FMQS, HALAL) for global quality recognitio. We have warehouses in coreports such as Qingdao, Tianiin, and Shanghai, with a 15-day express delivery service.

 

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Gneebio Product Packaging

 

Packaging Type Net Weight
Steel Drum 250 kg
IBC Tank 1250 kg
ISO Tank Bulk shipment

 

Dimethylacetamide solvent

 

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