What kind of solvent is acetonitrile Acn (cas 75 05 8)?
CAS 75-05-8 Acetonitrile (CH₃CN) is a polar, aprotic organic solvent. This means that it is polar, but lacks acidic protons. This makes it excellent for dissolving many substances, while remaining unreactive in certain reactions. It is a colourless liquid that is miscible with water. It is widely used in high-performance liquid chromatography (HPLC) and organic synthesis.
Acetonitrile is a solvent also known as methyl cyanide, cyanomethane, and ethanenitrile. It is colorless, volatile (bp 82 °C), flammable (flash point 2 °C), and toxic. It is miscible with water and most organic solvents except for some saturated hydrocarbons.
Acetonitrile Structure:


What is Acetonitrile solvent Used for?
- Acetonitrile is used as a solvent in the extraction process of hydrocarbons.
- It is used to separate fatty acids from vegetable oil.
- Used in making perfumes.
- It is widely used in the production of synthetic pharmaceuticals.
- It is used in the manufacturing of rubber.
- It is used in refining as well as extraction of copper.
- Used as a solvent in electrochemical cells.
Acetonitrile Solvent Handling
Precautions:
Handle acetonitrile in a well-ventilated area and, preferably, under a chemical fume hood to avoid inhaling vapours.
Avoid contact with skin, eyes and clothing.
Wear appropriate PPE, such as gloves, safety goggles and lab coats.
Incompatibilities:
Avoid contact with strong acids, bases, oxidising agents and reducing agents, as acetonitrile may react violently with these substances.
Hygiene measures:
Wash your hands and any other exposed skin thoroughly after handling acetonitrile. Do not eat, drink or smoke while handling this chemical.
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