What is CAS 75-05-8 Acetonitrile solvent?
Acetonitrile (CAS 75-05-8) is a chemical solvent with the chemical formula CH₃CN. Also known as Acn or methyl cyanide (MeCN). It is a colorless liquid with a pungent odor at room temperature. Acetonitrile has high solubility and volatility, making it widely used in chemical, pharmaceutical, metallurgical, and other industrial sectors.
| Item | Specification |
|---|---|
| Chemical Name | Acetonitrile |
| Other Names | ACN, Methyl Cyanide, MeCN |
| CAS No. | 75-05-8 |
| Molecular Formula | C₂H₃N |
| Molecular Weight | 41.05 |
| Purity | ≥99.9% |
| Appearance | Colorless transparent liquid |
| Boiling Point | 81–82℃ |
| Melting Point | -45℃ |
| Density | 0.786 g/cm³ |
| Flash Point | 12.8℃ |
| Solubility | Miscible with water and most organic solvents |
| UN Number | UN1648 |
| Hazard Class | Class 3 Flammable Liquid |


what is Acetonitrile ACN Solvent used for?
1. Chemical Engineering and Materials Industry
This is the most fundamental application field of acetonitrile, where it mainly functions as a solvent and reaction medium.
- As an organic synthesis solvent: As an organic synthesis solvent, acetonitrile is widely used as a reaction medium in pharmaceutical intermediates, specialty chemicals, and organic synthesis processes.
- As an extractant: In the petrochemical industry, it is used to separate butadiene and extract high-purity butadiene from C4 fractions (butadiene is a key raw material for manufacturing rubber and plastics).
- As a chromatographic analysis solvent: It is used as a mobile phase in high-performance liquid chromatography (HPLC) and is often applied to detect harmful substances in food and environmental samples.
2. Pesticide Industry
Acetonitrile C2h3n is a "key auxiliary agent" in pesticide synthesis, and it is irreplaceable especially in the production of high-purity products.
In the field of pesticide synthesis: Solvent Acetonitrile is used to manufacture herbicides (e.g., atrazine) and insecticides. It helps dissolve and react the active ingredients, thereby improving the stability and efficacy of pesticides.
3. Electronics and Semiconductor Industry
High purity acetonitrile is used in advanced electronic applications, including:
- Semiconductor processing and cleaning applications
- Lithium battery electrolyte formulations
- Specialty electronic chemical production
Its excellent purity and low impurity level make it suitable for applications requiring strict contamination control.
4. Pharmaceutical Industry
Acetonitrile is widely used in pharmaceutical manufacturing:
- API synthesis
- Pharmaceutical intermediates
- Reaction solvent
- HPLC mobile phase preparation
5. Laboratory and Analytical Applications
High purity acetonitrile is commonly used for:
- HPLC analysis
- LC-MS testing
- Sample preparation
- Chemical analysis
Why Choose gneebio?
At GNEE BIO, we provide reliable acetonitrile CAS 75-05-8 supply solutions for customers worldwide.
Stable Quality Control
We supply high purity acetonitrile with consistent quality and provide: COA, SDS, TDS, Batch quality documents, Flexible Packaging Options.
Available packaging includes:
- Steel drums
- IBC tanks
- ISO tanks
Global Export Experience
With professional export experience, GNEE BIO supports:
- International shipping
- Dangerous goods documentation
- Customized supply solutions
Reliable Bulk Supply
We cooperate with qualified production partners to ensure stable supply capacity for industrial and commercial customers.
Frequently Asked Questions About Acetonitrile CAS 75-05-8
Q: What Is Acetonitrile Used For?
A: Acetonitrile is a widely used organic solvent in industries such as pharmaceuticals, chemical synthesis, HPLC laboratory analysis, agrochemicals, and lithium battery production.
Because of its strong solvency, low viscosity, and high chemical stability, it is especially suitable for high-precision analytical testing and industrial purification processes.
Q: What Purity of Acetonitrile Do I Need for My Application?
A: This is one of the most important questions for buyers.
- HPLC/LC-MS grade (≥99.9%): required for analytical testing and laboratory use
- Electronic or battery grade: used in lithium battery electrolyte and high-end electronics
- Industrial grade: suitable for chemical synthesis and large-scale manufacturing
Choosing the correct grade directly affects product performance and test accuracy.
Q: How Stable Is Acetonitrile During Storage and Transport?
A: Acetonitrile is relatively stable under normal conditions, but buyers often care about:
- Moisture sensitivity (should be stored in tightly sealed containers)
- Compatibility with packaging materials
- Shelf life under different temperatures
- Risk of contamination during long-distance shipping
Proper storage in sealed steel drums or ISO tanks is recommended to maintain purity.
Q: What Are the Main Safety Precautions When Handling Acetonitrile?
Although acetonitrile is widely used, it should still be handled with care:
- Avoid inhalation of vapors and direct skin contact
- Use in well-ventilated areas or fume hoods
- Wear appropriate personal protective equipment (PPE) such as gloves and goggles
- Keep away from open flames and high heat sources
Proper handling reduces occupational exposure risks.
Q: What Packaging Options Are Available for Bulk Purchase?
For industrial buyers, packaging is a key purchasing concern. Common options include:
- 160 kg steel drums
- 800–1000 kg IBC tanks
- ISO tank containers for large-volume shipments
The choice depends on order volume, storage capacity, and transportation method.
Q: How Can I Ensure Consistent Quality Between Batches?
To ensure consistency, GNEE BIO can provide:
- COA (Certificate of Analysis) for every batch
- Third-party quality testing reports if required
- Stable production source and controlled raw materials
- Clear specification standards (purity, water content, acidity, etc.)
Contact Us:
Email: sales@gneebio.com
Website: https://www.gneebio.com/inquiry
Our company
GNEE BIO is a professional chemical raw material supplier and exporter based in Henan, China. We provide stable supply of solvents and specialty chemicals for global customers. With self-managed import and export rights, we support international trade with quality documents, flexible packaging options, and professional logistics services.

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