CAS 127-19-5 Dimethylacetamide (DMAC), (chemical formula: CH3C(O)N(CH3)2, abbreviated as Dmac or DMA. A commonly used aprotic polar solvent. Colorless transparent liquid, flammable. Can be used with Organic solvents such as water, alcohol, ether, ester, benzene, chloroform and aromatic compounds can be mixed at will. It is used in pharmaceuticals, synthetic resins, and is also used as a solvent for polyacrylonitrile spinning and the extraction of styrene from the carbon eight fraction. Distilled solvents, etc. are produced by the action of diamine and acetyl chloride.
Chemical Name: Dimethylacetamide
Abbreviation: DMAC / DMAc
CAS Number: 127-19-5
Molecular Formula: C₄H₉NO
Molecular Weight: 87.12 g/mol
Appearance: Colorless to light yellow transparent liquid
Odor: Slight amine-like odor
DMAC CAS 127-19-5 Dimethylacetamide Toxicity
Acute Toxicity
DMAC exhibits moderate toxicity and should be handled with appropriate industrial precautions.
Oral (rat) LD₅₀: ~4,000 mg/kg
Dermal (rabbit) LD₅₀: >2,000 mg/kg
Inhalation: High vapor exposure may cause respiratory irritation
Health Effects
Skin contact: May cause irritation or dryness after prolonged exposure
Eye contact: Causes irritation; splashes should be avoided
Inhalation: Vapors may cause dizziness, headache, or nausea
Chronic exposure: Prolonged exposure may affect the liver
Transport and Handling Information
Flash Point: 70°C (158°F) - Flammable liquid.
Storage: Store in a well-ventilated, cool, dry place. Keep containers tightly closed away from heat sources, sparks, and open flames.
Hazard Category: Typically classified as a flammable liquid during transport.
Protective Equipment: Use gloves and safety goggles. Wear respiratory protection in poorly ventilated areas.
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