Acetonitrile (CAS 75-05-8) is a polar aprotic solvent widely used in organic synthesis and chromatographic applications. It is known for its excellent solvating properties, particularly in high-performance liquid chromatography (HPLC), and is miscible with water and most organic solvents.
Is acetonitrile an organic solvent?
Yes, acetonitrile (CH3CN) also known as methyl cyanide, is a widely used polar aprotic organic solvent, recognizedas the simplest organic nitrile.
- Other Names: Methyl cyanide, Cyanomethane
- CAS Number: 75-05-8
- Chemical Formula: C₂H₃N
- Molar Weight: 41.05 g/mol
- Appearance: Clear, colorless liquid
Properties of Acetonitrile CAS 75-05-8:
| Odor | Faint pungent odor |
| Purity | 99% Min |
| Density (20℃) | 0.786 g/cm³ |
| Boiling Point | 81.6 ℃ |
| Melting Point | -48 ℃ |
| Flash Point | 5 ℃ |
| Solubility | Miscible with water, alcohol and organic solvents |
| Characteristic | Polar aprotic, high volatility |
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Are acetonitrile and methyl cyanide the same?
Yes, acetonitrile and methyl cyanide are the exact same chemical compound. They share the same chemical formula (C₂H₃N), structure (a methyl group attached to a nitrile group), and CAS number: 75-05-8.
Acetonitrile/methyl cyanide is a highly volatile, aprotic polar organic solvent. ACN or MeCN is used in analytical chemistry as a solvent or mobile phase.
Organic Solvent Acetonitrile Applications
1. Chromatography: Methyl Cyanide is used as a mobile phase in HPLC due to low UV absorbance and high elution strength.
2. Organic Synthesis: Serves as a solvent and reagent in various chemical reactions.
3. Extraction Processes: Applied in the extraction and purification of organic compounds.
4. Battery Industry: Acetonitrile ACN solvent is used in electrolyte formulations for lithium-ion batteries.
Storage of Acetonitrile chemical
- Environmental Sensitivity Control: Acetonitrile liquid is sensitive to light and high temperatures and must be kept away from direct sunlight to prevent physical degradation.
- Temperature Requirements: Classified as a Group IB flammable liquid, it must be stored below 23°C (73°F).
- Packaging and Storage Location: In accordance with OSHA regulations, acetonitrile should be stored in sealed metal containers, and all stock should be placed in fume hoods.
- Ventilation Management: Continuous mechanical ventilation is crucial to reduce vapor buildup and eliminate flammable and explosive catalysts.
- Fire and Hazard Prevention: Large-volume storage presents a significant flammability risk. A professional temperature control system helps maintain chemical stability, prevent exposure to toxic substances, and eliminate fire hazards.
- Leakage and Contamination Protection: Storage cabinets should be equipped with bottom leak control systems to prevent leaks and environmental contamination.
- Professional Support: Please contact Gneebio (professional supplier) for customized safe storage solutions for bulk acetonitrile and other flammable liquids.
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