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Tert-Butyl Methyl Ether (MTBE) - High Purity Solvent CAS 1634-04-4

Sep 17, 2025 Leave a message

 

Tert-Butyl Methyl Ether (MTBE) possesses unique physicochemical properties that make it an indispensable reagent in numerous industrial and laboratory processes.

 

What is Tert-Butyl Methyl Ether CAS 1634-04-4

Tert-Butyl Methyl Ether also known as Methyl tert-butyl ether (MTBE), CAS No. 1634-04-4, is a volatile, flammable ether compound with the molecular formula C₅H₁₂O. Due to environmental concerns, its use as an additive is gradually declining, while its role as a premium solvent in fine chemical synthesis, analytical chemistry, and pharmaceutical production is becoming increasingly significant. High-purity MTBE (typically ≥99.9%) is an indispensable key raw material for these precision applications.

 

Physical and Chemical Properties of MTBE:

CAS number: 1634-04-4
Chemical formula: C5H12O
Molar mass: 88.150 g·mol−1
Appearance: colourless liquid
Density: 0.7404 g/cm³
Melting point: −109 °C (−164 °F; 164 K)
Boiling point: 55.2 °C (131.4 °F; 328.3 K)
Solubility in water: 26 g/L (20 °C)[1]
Viscosity: 0.36 cP at 25 °C

 

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What is MTBE also known as?

MTBE is an acronym for Methyl tert-butyl ether, the most commonly used name for this organic ether compound.
Synonyms: Methyl t-butyl ether, methyl tert-butyl ether, tert-butyl methyl ether, and 2-methoxy-2-methylpropane.

 

What is Tert-Butyl Methyl Ether (MTBE) solvent used for?

Extraction Processes:
Methyl Tert-butyl Ether MTBE is exceptionally effective in liquid-liquid extraction, particularly in the isolation of natural products. Its low density, low water solubility, and high selectivity make it ideal for separating organic compounds from aqueous matrices.

  • Extraction of plant oils, fragrances, and flavors.
  • Isolation of active pharmaceutical ingredients (APIs) from fermentation broths.
  • Analytical chemistry

 

Chromatography:
In high-performance liquid chromatography (HPLC) and flash chromatography, high-purity Tert-Butyl Methyl Ether (MTBE) is frequently used as a mobile phase component.

 

Specialized Cleaning Agent:
Due to its strong solvency power for greases, oils, and adhesives, and its ability to evaporate without leaving a residue, Tert-Butyl Methyl Ether (CAS 1634-04-4) is used in precision cleaning applications for electronic components and mechanical parts.

 

Tert-Butyl Methyl Ether Solvent

 

Safety

  • Tert-Butyl Methyl Ether is flammable and should be kept away from open flames or high-temperature substances. Store in a cool, well-ventilated area.
  • Avoid inhaling vapors and prevent contact with skin and eyes.
  • Methyl tert-butyl ether may adversely affect the environment; therefore, comply with relevant environmental protection regulations during use and handling.
  • In industrial production processes, implement appropriate safety measures, including wearing personal protective equipment such as safety goggles, respirators, and protective gloves.

 

 

Conclusion

MTBE (CAS 1634-04-4) is a versatile high-purity solvent, leveraging low boiling point, miscibility, and low reactivity for synthesis, pharmaceuticals, analytics, and electronics.

 

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Tert-Butyl Methyl Ether (MTBE)

 

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