Products Description
Acetyl chloride (CH₃COCl, also written C₂H₃ClO) is a colourless liquid with a pungent odour, miscible with most organic solvents such as diethyl ether and petroleum ether. It is one of the most important acetylation reagents in organic synthesis: the acetyl group (CH₃CO–) is transferred to alcohols, amines and other nucleophiles to form esters, amides and acetylated derivatives. This page provides the technical specification and safe-handling guidance.
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specification
| Item | Value |
|---|---|
| Product name | Acetyl chloride |
| CAS number | 75-36-5 |
| Molecular formula | CH₃COCl (C₂H₃ClO) |
| Molecular weight | 78.50 |
| Purity | ≥ 99% |
| Appearance | Colourless transparent liquid |
| Density (25°C) | ≈ 1.104 g/mL |
| Boiling point | ≈ 52°C |
| Application | Organic synthesis (acetylation) |


Applications:
- Acetylation reagent: acetyl chloride acylates alcohols, phenols, amines and other nucleophiles to produce esters, amides and acetylated derivatives.
- Pharmaceutical synthesis: intermediate in the manufacture of acetylated drug substances and their precursors.
- Dye and fine-chemical synthesis: used in the production of dyes and other acetyl-containing compounds.
Storage
Store in a cool, dry, well-ventilated warehouse, away from ignition sources and heat. The container must be tightly sealed to exclude moisture. Store separately from oxidizers, alcohols, bases and other incompatible substances - do not store together. (Acetyl chloride reacts with water and alcohols; moisture ingress causes decomposition with hydrogen-chloride evolution.)
Safety and Handling Information
Acetyl chloride is a hazardous chemical and must be handled accordingly:
- Reactivity: reacts violently with water and alcohols, releasing heat and hydrogen chloride gas; keep strictly dry and add to water never in reverse (quench by slow addition to a large excess of cold water with agitation, or use a proper quenching procedure).
- Flammability: flammable liquid (flash point about 4°C, closed cup); keep away from ignition sources.
- Corrosivity: causes burns to skin, eyes and respiratory tract; vapours are irritating and corrosive. Use chemical-resistant gloves, goggles and protective clothing, with adequate ventilation.
- Transport: classified under UN 1717 (Acetyl chloride, flammable liquid, corrosive); transport in accordance with dangerous-goods regulations.
- Documentation: the Safety Data Sheet (SDS) must be consulted and supplied with every shipment; comply with local chemical regulations.
Why choose GNEE BIO?
1. Can provide high quality and competitive price.
2. Free samples for your evaluation.
3. Use the local transportation company to transport the goods, so that you can receive the goods quickly.
4. We will inform you all the information of each stage in advance.
5. Packaging can be customized.
6. Respond at the first time before and after sale.
Packaging
- 200 kg iron drum
- IBC tank (1000 L)
- ISO Tank
- Customizable labels and packaging; OEM / ODM service

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Company Profile
GNEE BIO is a professional supplier and exporter of chemical raw materials, with over 10 years of experience in international trade. We work with qualified manufacturing partners to provide reliable products, competitive prices, and stable supply.
We provide COA, MSDS, TDS, export documentation, and other services to support customers worldwide.
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Our best-selling products include: Dimethyl Sulfoxide (DMSO), Dichloromethane, Glacial Acetic Acid, Methyl Acetate, Ethanol, Ethylene Glycol, Triethylene Glycol, N,N-Dimethylacetamide (DMAC), Methyl Formate, and Cyclohexanone.



FAQ
Q1: Quality Assurance
A1: GNEE BIO strictly controls the quality of the products, and all products comply with relevant national standards to ensure that it provides customers with the highest quality products.
Q2:Lead-time and Freight
A2: Only need 1-3 workdays for most goods in stock. Delivery time is around 3-7 business days by DHL,FedEx,UPS.Experienced freight forwarders arrange shipment for us, with low price and first-class service.
Q3:Terms of Payment
A3: T/T, 30% deposit will be required before the mass production and 70% balance which will be paid before sending the order.
Q4:Sample order
A4:We accept sample order.Free sample can be supplied if need.
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