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What is acetonitrile (CAS 75-05-8) used for in pharmaceutical industry?

Mar 05, 2026 Leave a message

Acetonitrile CAS 75-05-8 is widely used in the pharmaceutical industry as a solvent for drug synthesis, analytical testing, and purification processes. It is particularly important in high-performance liquid chromatography (HPLC), where it serves as a mobile phase solvent for drug analysis and quality control.

 

Usage Examples in the Pharmaceutical Industry:

  • HPLC: Used as a mobile phase for compound separation, with low viscosity and strong UV transparency.
  • API Synthesis & Purification: Solvent for manufacturing insulin, antibiotics, and vitamins A & B1.
  • Extraction Solvent: Extracts fatty acids and purifies pharmaceuticals and steroids.
  • Reaction Medium: Polar solvent for organic reactions including coupling reactions.
  • Laboratory Reagent: Used in DNA/RNA synthesis and non-aqueous titrations.

 

Process Role of Acetonitrile
API synthesis Reaction solvent
Chromatographic analysis Mobile phase
Drug impurity testing Analytical solvent
Compound purification Extraction solvent

 

 

History has shown that acetonitrile CAS 75-05-8 is practically irreplaceable in many industries, the most critical of which is the pharmaceutical industry. Its chemical structure make it uniquely suited as an analytical reagent, reaction solvent, and synthetic substrate – especially as a nitrogen or cyanide source in medicinal compounds. Many critical applications of acetonitrile require high purity, USP grade chemicals that cannot be obtained via recycled waste.

 

 

Looking for a reliable Pharmaceutical Grade Acetonitrile Solvent Supplier or manufacturer? Contact us for bulk supply, COA, SDS and competitive pricing.

 

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High-Purity Acetonitrile Solvent Supplier

 

about us

As a leading manufacturer and exporter of fine chemicals, Henan Gneebio provides high-quality industrial chemicals. We supply to customers across the chemical, pharmaceutical, and materials industries, ensuring consistent quality, reliable logistics, and professional technical support.

Our chemical products hold international certifications (REACH, ISO, FMQS, HALAL) for global quality recognitio. We have warehouses in coreports such as Qingdao, Tianiin, and Shanghai, with a 15-day express delivery service.

 

Other Hot-Selling Products

 

CAS 64-19-7 Acetic acid/Glacial Acetic Acid; CAS 67-68-5 Dimethyl Sulfoxide (DMSO); CAS 67-63-0 Isopropyl alcohol (IPA); CAS 95-47-6 o-Xylene; CAS 106-42-3 p-Xylene; CAS 75-09-2 Dichloromethane (DCM).

 

 

Gneebio Product Packaging

 

Packaging Type Net Weight
Steel Drum 160 kg
ISO Tank 20–22 MT
IBC Tank 800–1000 kg

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