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Why is dimethylacetamide DMAC used as a solvent?

Mar 13, 2026 Leave a message

Dimethylacetamide DMAC (CAS No 127-19-5) is extensively employed for dissolving polymers (such as acrylic esters and polyurethanes) and in pharmaceutical synthesis. Its miscibility with most organic solvents and water makes it an ideal choice for fiber spinning and as a reaction medium.

 

Dimethylacetamide (DMAc) Solvent Specifications

Product Name N,N-Dimethylacetamide
Synonyms DMAc, DMA, dimethyl acetamide
CAS Number 127-19-5
Molecular Formula C₄H₉NO
Molecular Weight 87.12 g/mol
Appearance Colorless transparent liquid
Purity (GC) ≥ 99.5%
Density (20°C) 0.936 g/cm³
Boiling Point 164–166 °C
Melting Point −20 °C
Flash Point 66–70 °C (Closed Cup)
Refractive Index (20°C) 1.437–1.439
Water Content ≤ 0.05%
Acidity (as Acetic Acid) ≤ 0.005%
Residue on Evaporation ≤ 0.005%
Color (APHA) ≤ 10
Solubility Miscible with water and most organic solvents
Vapor Pressure 1.3 mmHg (20 °C)

 

 

Why is dimethylacetamide used as a solvent?

High Solubility
DMAc dissolves polymers (such as polyurethane, polyimide, polyacrylonitrile) that conventional solvents cannot process, thereby enhancing reaction efficiency and formulation stability.

 

High Boiling Point and Stability
With a boiling point of approximately 165°C, DMAc remains stable at elevated temperatures.

 

Highly Efficient Polar Non-Protonic Solvent
As a polar non-protonic solvent, it stabilizes reaction intermediates, accelerates pharmaceutical and polymerization processes, and improves yields.

 

Excellent Polymer Compatibility
It exhibits good miscibility with various industrial polymers, facilitating the preparation of uniform solutions and high-quality fibers, coatings, and films.

 

Recyclable and Cost-Effective
DMAc can be recycled and reused, reducing solvent consumption and lowering costs.

 

 

 

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Gneebio Product Packaging

 

Packaging Type Net Weight
Steel Drum 160 kg
ISO Tank 20–22 MT
IBC Tank 800–1000 kg

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