Yes, ethyl ethanoate/ethyl acetate (CAS 141-78-6) is classified as a Class 3 residual solvent under the ICH (International Council for Harmonisation) Q3C guidelines and USP.
What is a Class 3 solvent?
According to ICH Q3C (Residual Solvents Guidance): Class 3 solvents are low-toxicity solvents, considered safer, and suitable for pharmaceutical applications. Class 3 solvents are preferred when concentrations are higher than Class 1 or Class 2 solvents, and when minimizing toxicity is required and stricter controls are not necessary compared to Class 1 (highly toxic) or Class 2 (toxic) solvents.
CAS 141-78-6 Ethyl Acetate Solvent Classification
- ICH Q3C Classification: Class 3
- Permitted Daily Exposure (PDE): 50 mg/day (typical guideline)
- Toxicity: Low; generally safe in controlled quantities
Ethyl acetate is widely used as a residual solvent in pharmaceutical manufacturing and food-grade applications.
Applications of Class 3 Ethyl Acetate Solvent
1. Paints, Coatings, and Inks
Largest consuming industry (especially in Asia). Ethyl acetate serves as a fast-evaporating solvent in paints, varnishes, and inks, enabling rapid drying and suitable for high-speed printing and spraying.
2. Adhesives and Packaging
Used in adhesives, sealants, and flexible packaging. Can be made into strong adhesives and fast-drying inks for packaging films/foils.
3. Pharmaceuticals and Cosmetics
Accounts for approximately 8-10% of global demand. Used in pharmaceutical purification; used in nail care and perfumes, characterized by rapid evaporation.
4. Food and Beverages
Used for caffeine and flavor extraction. Small amounts are safe for use as a fruit flavoring agent.
Get Your Quote or Place Your Order Today!
High-Purity Ethyl Acetate/EtOAc Solvent CAS 141-78-6 Supplier
about us
As a leading manufacturer and exporter of fine chemicals, Henan Gneebio provides high-quality industrial chemicals. We supply to customers across the chemical, pharmaceutical, and materials industries, ensuring consistent quality, reliable logistics, and professional technical support.
Our chemical products hold international certifications (REACH, ISO, FMQS, HALAL) for global quality recognitio. We have warehouses in coreports such as Qingdao, Tianiin, and Shanghai, with a 15-day express delivery service.
Other Hot-Selling Products
| Dimethyl Sulfoxide (DMSO) | CAS 67-68-5 |
| Dichloromethane / Methylene Chloride | CAS 75-09-2 |
| Glacial Acetic Acid / Ethanoic Acid | CAS 64-19-7 |
| Ethyl Acetate / Ethyl Ethanoate | CAS 141-78-6 |
| Ethylene Glycol / Monoethylene Glycol (MEG) | CAS 107-21-1 |
| Trichloroethylene | CAS 79-01-6 |
| Cyclohexanone | CAS 108-94-1 |
Gneebio Product Packaging
| Packaging Type | Net Weight |
|---|---|
| Steel Drum | 250 kg |
| IBC Tank | 1250 kg |
| ISO Tank | Bulk shipment |
Customer Visit
