Knowledge

What is dimethyl acetamide cas no 127-19-5 used for?

Mar 12, 2026 Leave a message

Dimethyl acetamide cas no 127-19-5 is a high-performance polar aprotic solvent extensively used in the chemical industry for producing acrylic fibers, spandex, and polyamides. It serves as a reaction medium in pharmaceutical manufacturing, a solvent for paints, and an agent in adhesives and electronics.

 

DMAc Technical Data Sheet

 

Parameter Specification
Product Name N,N-Dimethylacetamide
Other Names DMAc, Dimethyl acetamide
CAS Number 127-19-5
Molecular Formula C₄H₉NO
Molecular Weight 87.12 g/mol
Appearance Colorless transparent liquid
Purity ≥99.5%
Density 0.936 g/cm³ (20°C)
Boiling Point 164–166°C
Melting Point −20°C
Flash Point 66–70°C (Closed cup)
Refractive Index 1.437–1.439 (20°C)
Solubility Miscible with water and most organic solvents
Vapor Pressure 1.3 mmHg (20°C)
Water Content ≤0.05%
Acidity (as Acetic Acid) ≤0.005%
Residue on Evaporation ≤0.005%

 

 

What is dimethyl acetamide cas no 127-19-5 used for?

Dimethylacetamide (DMAC) is a high-boiling-point, polar non-protonic solvent characterized by strong solubility, excellent thermal and chemical stability, and low corrosivity. It finds extensive applications across numerous industries as a critical reaction medium, processing solvent, and cleaning agent.

 

In the fiber and textile industry, dimethyl acetamide (CAS No. 127-19-5) is primarily used in the production of spandex, acrylic, aramid fibers, and cellulose-based materials. It serves as a key spinning solvent in both wet and dry spinning processes.

 

In pharmaceutical applications, Dimethylacetamide Solvent serves as a vital solvent and reaction medium for synthesizing, crystallizing, and purifying active pharmaceutical ingredients, antibiotics, peptides, and contrast agents. It is also employed in manufacturing medical dialysis membranes.

 

In polymer and plastics production, DMAC dissolves and processes high-performance polymers like polyimides, polysulfones, and polyamides. It also serves in adhesive and coating formulations, as well as graphene exfoliation processes.
Within the electronics industry, its high cleaning efficiency and gentle impact on equipment make it widely used for wafer cleaning, photoresist stripping, LCD manufacturing, and printed circuit board processing.

 

In petrochemical and chemical synthesis applications, dimethyl acetamide (CAS No. 127-19-5) serves as an extraction solvent for separating hydrocarbon mixtures, facilitates natural gas desulfurization and decarbonization, and functions as a high-temperature reaction solvent in coupling, condensation, and acylation reactions.

 

Dimethylacetamide uses

 

Why Industrial Buyers Choose DMAc solvent?

For chemical manufacturers and industrial buyers, DMAc presents numerous notable advantages.
1. Dimethyl acetamide cas no 127-19-5 exhibits outstanding solvency capabilities, enabling it to dissolve a wide range of substances such as polymers, inorganic salts, and various organic compounds.
2. Featuring a boiling point of approximately 165°C, DMAc is well‑suited for high‑temperature chemical reactions and industrial processing.
3. Additionally,dimethylacetamide solvent demonstrates strong chemical stability under diverse reaction conditions, rendering it highly reliable for complex chemical synthesis.

 

Which industries use DMAC solvent?

Industry Use
Polymer manufacturing Polyurethane, polyimide, fibers
Pharmaceuticals Reaction solvent for synthesis
Electronics Battery and semiconductor materials
Chemical manufacturing Specialty reactions and intermediates
Coatings and adhesives Resin and formulation solvent

 

Safe handling and Storage

 

Safe Handling Use adequate ventilation, wear protective gloves and goggles, and adopt closed transfer systems.
Storage Store in sealed containers, keep in cool and well-ventilated areas, and keep away from oxidizing agents.

 

 

Looking for a reliable dimethylacetamide solvent (CAS 127-19-5) Supplier or manufacturer? Contact us for bulk supply, COA, SDS and competitive pricing.

 

Get Your Quote or Place Your Order Today!

 

High-Purity DMAC Solvent Supplier

 

 

FAQ

Why is DMAc used as a solvent?

Dimethyl acetamide DMAC is a dipolar aprotic solvent used for many organic reactions and industrial applications. It is a versatile solvent due to its high boiling point and good thermal and chemical stability.

 

Is dimethylacetamide used in pharmaceutical industry?

N,N-Dimethylacetamide DMAC solvent is an important pharmaceutical raw material widely used in the production of drugs such as amoxicillin and cephalosporins. It acts as a solvent or co-catalyst and offers improved product quality and yield compared to traditional organic solvents.

DMAC plays a vital role in manufacturing pharmaceutical intermediates and active pharmaceutical ingredients (APIs).

 

What purity grades of dimethylacetamide are available?

DMAc is available in several grades depending on the application, including:

  • industrial grade
  • pharmaceutical grade
  • electronic grade
  • high-purity laboratory grade

Purity Levels: Common concentrations include 98.5%, 99%, 99.5%, 99.8%, and 99.9%.

 

about us

As a leading manufacturer and exporter of fine chemicals, Henan Gneebio provides high-quality industrial chemicals. We supply to customers across the chemical, pharmaceutical, and materials industries, ensuring consistent quality, reliable logistics, and professional technical support.

Our chemical products hold international certifications (REACH, ISO, FMQS, HALAL) for global quality recognitio. We have warehouses in coreports such as Qingdao, Tianiin, and Shanghai, with a 15-day express delivery service.

 

Other Hot-Selling Products

 

CAS 64-19-7 Acetic acid/Glacial Acetic Acid; CAS 67-68-5 Dimethyl Sulfoxide (DMSO); CAS 67-63-0 Isopropyl alcohol (IPA); CAS 95-47-6 o-Xylene; CAS 106-42-3 p-Xylene; CAS 75-09-2 Dichloromethane (DCM).

 

 

Gneebio Product Packaging

 

Packaging Type Net Weight
Steel Drum 160 kg
ISO Tank 20–22 MT
IBC Tank 800–1000 kg

dimethylacetamide Chemical Manufacturer

Customer Visit

dimethylacetamide for sale

Send Inquiry