What is Flunixin Meglumine injection?
Flunixin Meglumine Injection is used to reduce pain and inflammation and control fever in many species of animals like cats, cows, dogs, goats, horses. poultry, sheep, and pigs. It relieves symptoms associated with conditions like bovine respiratory disease, endotoxemia, or acute mastitis. It is also used to treat musculoskeletal pain and visceral pain associated with colic.
Can Flunixin Meglumine be given intramuscular?
Flunixin meglumine may be given intramuscularly or intravenously:
The dose is determined by body weight.
Beef cattle and swine require 0.4 ml per 10 kg body weight, while dogs and cats require 0.2 to 0.4 ml per 10 kg body weight.
For dogs and cats, 0.2 to 0.4 ml per 10 kg body weight is recommended.
Injections should be given once or twice a day for no more than 5 consecutive days to ensure efficacy and safety.
How does Flunixin Meglumine function pharmacologically?
Flunixin meglumine inhibits the enzyme cyclooxygenase (COX), which is essential for prostaglandin synthesis to help reduce pain, fever, and inflammation. It affects both COX-1 and COX-2 isoenzymes, which are implicated in inflammatory response and homeostasis.
Precautions
Do NOT use Flunixin Meglumine Injection for an animal that:
has a known allergy or hypersensitivity to any of the ingredients.
-is a dairy cow in the dry period.
-is a calf intended to be slaughtered for veal.
-is a horse intended for human consumption.
-is a bull intended for breeding.
-has severe kidney dysfunction or dehydration.
-has pre-existing ulcerative gastrointestinal lesions.