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How is acetonitrile ACN CAS 75-05-8 manufactured?

Dec 16, 2025 Leave a message

CAS 75-05-8 Acetonitile ACN, also known as methyl cyanide or ethanenitrile,is a chemical compound with the formula c2H3N.1t is a colorless, volatileliquid with a faintether-like odor. Acetonitrle ls widely used in varous industies due to its sovent propeties, hioh boling point and ablty to dissove a range of polar and nonpolar substances.

 

CAS number:  75-05-8

 

Structure:

 

CAS number 75-05-8  Acetonitrile Structure:

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How is acetonitrile ACN CAS 75-05-8 manufactured?

CAS 75-05-8 Acetonitrile can be synthesized via four main industrial routes, each with distinct reactants and conditions:

 

1. Ethylene Cyanation: Ethylene reacts with sodium cyanide or potassium cyanide under high temperature and pressure to directly produce acetonitrile. This route is widely used for large-scale production due to its high efficiency.

 

2. Ethanol Dehydration: Ethanol undergoes reaction with concentrated sulfuric acid or phosphoric acid (serving as catalysts) to form acetonitrile through dehydration and rearrangement processes.

 

3. Propionitrile Hydrolysis: Propionitrile is hydrolyzed in the presence of acid or base catalysts, breaking down to generate acetonitrile as the key product.

 

4. Formamide Reaction: Formamide reacts with aqueous ammonia via a series of chemical transformations, including condensation and rearrangement, to yield acetonitrile. This method is favored for its moderate reaction conditions.

 

 

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Acetonitrile Chemicals

 

Organic Solvent Acetonitrile (ACN)

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