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What are the hazardous properties of acetonitrile (cas 75 05 8)?

Dec 16, 2025 Leave a message

What are the properties of acetonitrile?

NAME: Acetonitrile (ACN)

Synonyms: Cyanomethane / Methyl cyanide (MeCN) / Ethanenitrile / Ethyl nitrile / Methanecarbonitrile

Molecular Formula: C2H3N

Molecular Weight: 41.052

CAS NO.: 75-05-8

 

Colorless, transparent liquid, flammable, its vapor can form explosive mixture with air, and there is a danger of combustion and explosion when exposed to open flame, high heat or contact with oxidants. It can dissolve some inorganic salts, such as silver nitrate, lithium nitrate and magnesium bromide. Acetonitrile ACN can dissolve many unsaturated hydrocarbons, but not saturated hydrocarbons. It can react strongly with oxidants to form explosive mixtures.

 

structure

CAS number 75-05-8  Acetonitrile Structure:

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What are the hazardous properties of acetonitrile (cas 75 05 8)?

Flammability: Class IB flammable liquid (flash point: 6°C). Its vapour can form explosive mixtures with air.

 

Toxicity:

Acute: Inhalation or ingestion may result in headaches, dizziness, nausea, vomiting, convulsions and coma. The primary acute risk is from its metabolite, cyanide.

 

Metabolism: It is metabolised in the liver by cytochrome P450 enzymes, releasing hydrogen cyanide. This delayed toxicity can take several hours to manifest, making it particularly dangerous.

 

Chronic: Prolonged skin contact or inhalation can cause irritation and systemic effects.

 

Environmental hazard: Toxic to aquatic life.
 

Safety Information

  • Ventilation: Use in well-ventilated areas, especially unventilated spaces like trenches.
  • Ignition Sources: Keep away from heat, sparks, flames, and hot surfaces.
  • Protective Gear: Wear gloves (chemically resistant), eye protection, and appropriate clothing.
  • Storage: Store in fireproof, well-ventilated areas, away from acids, bases, and oxidizers

 

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Acetonitrile Chemicals

 

Organic Solvent Acetonitrile (ACN)

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