Is diethylene glycol (DEG CAS 111-46-6) safe?
DEG is toxic to humans. Glycol/diethylene glycol breaks down in the body into toxic compounds that first affect the central nervous system (CNS), then the heart, and finally the kidneys. Ingesting enough ethylene glycol can cause death.
Toxicity of Diethylene Glycol
1. Oral toxicity: DEG is toxic when ingested. Ingestion of certain amounts can cause severe damage to the body, affecting the central nervous system, kidneys, liver and other organs. Symptoms may include nausea, vomiting, abdominal pain, dizziness, headache, and in severe cases, organ failure and even death.
2. Skin absorption and eye contact: Prolonged or excessive skin contact with DEG may cause skin sensitization, redness and itching. Contact with the eyes can cause eye irritation, pain, and possible damage to the cornea.
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