CAS 141-78-6 Ethyl acetate (EtOAc) and CAS 67-64-1acetone are both widely used organic solvents in industries such as coatings, pharmaceuticals, adhesives, and cleaning agents. They share some similar properties, and many purchasing professionals often ask: Are ethyl acetate and acetone the same?
The answer is: While they share some similarities, they differ significantly in chemical structure, polarity, solubility, and applications.

Key Properties of Ethyl Acetate (EtOAc)
Ethyl acetate (EtOAc) also known as ethyl ethanoate, is a clear, colorless liquid with a sweet, fruity aroma. It is an ester compound (C4H8O2) formed by the reaction of ethanol and acetic acid. Its properties are as follows:
- Physical and Chemical Properties: Boiling point approximately 77°C, flash point -4°C, density 0.89 g/mL.
- Solubility: Moderate, capable of dissolving many resins and polymers.
- Volatile Rate: Fast (vaporization rate is 4.1 relative to butyl acetate = 1).
- Odor and Toxicity: Mild fruity aroma; low toxicity, but high concentrations may irritate eyes and skin.
- Applications: Due to its balanced solubility and dissolving power, ethyl acetate (EtOAc) is widely used in coatings, inks, adhesives, pharmaceuticals, and cleaning products.
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Key Differences Between Ethyl Acetate and Acetone
| Ethyl Acetate | Acetone | |
|---|---|---|
| Chemical Type | Ester | Ketone |
| CAS Number | 141-78-6 | 67-64-1 |
| Molecular Formula | C₄H₈O₂ | C₃H₆O |
| Odor | Sweet, fruity | Sharp, pungent |
| Polarity | Medium | High |
| Evaporation Rate | Medium-fast | Very fast |
| Boiling Point (°C) | 77.1 | 56 |
| Solvency Strength | Good | Strong |
| Flammability | Highly flammable | Highly flammable |
| Typical Uses | Coatings, inks, food processing | Cleaning, degreasing, nail polish remover |
Key Differences Explained
1. Chemical Structure: Ethyl acetate chemicalis an ester, synthesized from ethanol and acetic acid; acetone is a ketone compound with a simpler molecular structure.
2. Solubility: Acetone has a stronger solubility, capable of dissolving a wider variety of substances; ethyl acetate (CAS 141-78-6) has a weaker solubility and higher selectivity. Therefore, acetone is suitable for heavy-duty cleaning, while EtOAc is better suited for precisely controlled industrial formulations.
3. Evaporation Rate: Acetone evaporates much faster than ethyl acetate, which evaporates more slowly, resulting in longer working times-a key advantage in coatings and printing applications.
4. Application Differences: Ethyl Ethanoate solvent is widely used in paints and coatings, printing inks, and food and pharmaceutical extraction processes. CAS 67-64-1 Acetone is mainly used in industrial cleaning and degreasing, paint stripping, and the production of nail polish removers.
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People also ask
Why is acetone cheaper than ethyl acetate?
Acetone is generally cheaper than ethyl acetate due to its simpler, high-volume production process, often as a byproduct of phenol manufacturing, and higher global industrial demand. However, due to fluctuations in raw material supply and demand, the price of acetone tends to fluctuate more dramatically.
What are common uses of Ethyl Acetate?
99% Purity Ethyl acetate solvent is widely used in numerous products across various industries. It is found in adhesives, various paints, industrial coatings, perfumes, and even food flavorings. Furthermore, it is used in cleaning and in the decaffeination process of tea and coffee.
Can Ethyl Acetate Replace Acetone?
In some applications, it can be used as a substitute. However, it is not a substitute in all situations.
- When strong, rapid dissolution is required, use acetone.
- When better control, lower odor, or safer handling is needed, use ethyl acetate.
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Gneebio Product Packaging
| Packaging Type | Net Weight |
|---|---|
| Steel Drum | 250 kg |
| IBC Tank | 1250 kg |
| ISO Tank | Bulk shipment |

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