Is tetrahydrofuran harmful?

What is Tetrahydrofuran THF (CAS 109-99-9)?

CAS 109-99-9 Tetrahydrofuran (THF) is a versatile organic solvent widely used in industrial, pharmaceutical, and chemical synthesis applications. It is a colorless, highly volatile, and water-miscible liquid with a low viscosity, making it an ideal solvent for polymers, resins, coatings, adhesives, and organic reactions. THF is also commonly used in Grignard reactions, lithium battery electrolytes, and industrial extraction processes.

Is tetrahydrofuran harmful?

Yes, tetrahydrofuran (CAS 109-99-9) is harmful. Its hazards are multi-faceted:

• Flammability: It is highly flammable with a very low flash point (-14°C).
• Health Effects: Harmful if inhaled, ingested, or absorbed through the skin, causing CNS depression and potential organ damage.
• Peroxide Formation: It can form highly unstable and explosive organic peroxides upon standing in air, which is a significant safety risk.

Safety Precautions

Keep the container tightly closed and store in a well-ventilated area.

Keep away from food, beverages, and animal feed.

Keep away from fire and do not smoke.

If contact with eyes, immediately flush with plenty of water and seek medical advice.

Wear appropriate protective clothing, gloves, and eye/face protection.

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