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What is Methyl Cyanide (CAS 75-05-8) used for in industry?

Jan 29, 2026 Leave a message

What Is Methyl Cyanide (CAS 75-05-8) ?

CAS 75-05-8 Methyl cyanide, more commonly known as Acetonitrile is a clear, colourless liquid with a sweet, ether like odour which has the chemical formula CH3CN. It is a by-product of acrylonitrile manufacture and it may also be formed by the combustion of wood and vegetation.

 

Methyl Cyanide is a volatile, highly polar solvent used to extract fatty acids and animal and vegetable oils. It is used in the petrochemical industry in extractive distillation based on its selective miscibility with organic compounds. It is used as a solvent for spinning synthetic fibres and in casting and moulding plastics. In laboratories, it is widely used in high-performance liquid chromatographic (HPLC) analysis and as a solvent for DNA synthesis and peptide sequencing.

 

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What is Methyl Cyanide (CAS 75-05-8) used for in industry?

Pharmaceutical Industry: Acetonitrile/Methyl Cyanide is used as a key solvent, it is widely used in the production of drugs and active pharmaceutical ingredients (APIs), as well as in the synthesis of DNA/oligonucleotides.

 

Analytical Chemistry (HPLC/GC): Due to its high purity and strong solvency, acetonitrile Acn is extensively employed as a mobile phase solvent in high-performance liquid chromatography (HPLC), gas chromatography (GC), and liquid chromatography-mass spectrometry (LC-MS).

 

Chemical Intermediates: Methyl Cyanide is used in the production of various organic chemicals, including acetamide hydrochloride, thiamine, and flavorings.

 

Battery Manufacturing: Serves as a solvent in lithium-ion batteries.

 

Electroplating: As a solvent for salts in metal deposition processes.

 

Other Applications: Employed in plastic production and photographic film manufacturing, also serving as a solvent for coatings and adhesives.

 

 

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