What is Florfenicol injection?
Florfenicol is a thiamphenicol derivative, which is similar in action to chloramphenicol. It works by inhibiting protein synthesis within the bacteria. Florfenicol displays a broad spectrum of antibacterial activity against gram-negative bacilli, gram-positive cocci, and atypical bacteria like Mycoplasma.
Florfenicol functions by targeting the ribosomes within the bacterial cell. Ribosomes are essential components for the synthesis of proteins, which are critical for cell growth and replication. By inhibiting the peptidyl transferase activity of the 50S ribosomal subunit, florfenicol disrupts protein synthesis within the bacterial cell, leading to cell stasis and ultimately cell death.
What is the function of florfenicol in poultry?
Florfenicol is an antibiotic widely used in poultry, particularly for treating and preventing bacterial infections affecting the respiratory and gastrointestinal tracts, like infections caused by Escherichia coli and Pasteurella multocida. Its broad-spectrum activity and effectiveness against various gram-negative and gram-positive bacteria make it valuable for combating common bacterial diseases in broilers and laying hens.
Precautions of Florfenicol Injection for poultry
- Prohibited during egg-laying period of laying hens.
- It is forbidden to use in vaccination period or animals with serious deficiency of immune function. Renal insufficiency need to reduce the amount or extend the time between doses.